7LGD

HLA-B*07:02 in complex with SARS-CoV-2 nucleocapsid peptide N105-113

Summary for 7LGD

• Entry DOI: 10.2210/pdb7lgd/pdb
• Descriptor: HLA class I histocompatibility antigen, B alpha chain, Beta-2-microglobulin, SARS-CoV-2 nucleocapsid peptide N105-113, ... (7 entities in total)
• Functional Keywords: sars-cov-2, hla, t cell, cross-reactivity, covid-19, antigen presentation, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 91400.72

Authors

Gras, S.,Szeto, C.,Chatzileontiadou, D.S.M. (deposition date: 2021-01-20, release date: 2021-04-21, Last modification date: 2023-10-18)

• Primary citation: Lineburg, K.E.,Grant, E.J.,Swaminathan, S.,Chatzileontiadou, D.S.M.,Szeto, C.,Sloane, H.,Panikkar, A.,Raju, J.,Crooks, P.,Rehan, S.,Nguyen, A.T.,Lekieffre, L.,Neller, M.A.,Tong, Z.W.M.,Jayasinghe, D.,Chew, K.Y.,Lobos, C.A.,Halim, H.,Burrows, J.M.,Riboldi-Tunnicliffe, A.,Chen, W.,D'Orsogna, L.,Khanna, R.,Short, K.R.,Smith, C.,Gras, S.; CD8 + T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses.; Immunity, 54:1055-, 2021; PubMed: 33945786; DOI: 10.1016/j.immuni.2021.04.006

Experimental method

X-RAY DIFFRACTION (2.88 Å)