Crystal Structure of CF34 TCR in complex with HLA-B8/FLR

Summary for 3FFC
DescriptorHLA class I histocompatibility antigen, B-8 alpha chain, Beta-2-microglobulin, FLRGRAYGL peptide from an EBV protein, ... (9 entities in total)
Functional Keywordstcr-peptide-mhc, glycoprotein, host-virus interaction, immune response, membrane, mhc i, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, immune system
Biological sourceHomo sapiens (Human)
Total number of polymer chains10
Total formula weight192377.27
Gras, S.,Burrows, S.R.,Kjer-Nielsen, L.,Clements, C.S.,Liu, Y.C.,Sullivan, L.C.,Brooks, A.G.,Purcell, A.W.,McCluskey, J.,Rossjohn, J. (deposition date: 2008-12-03, release date: 2009-01-27, Last modification date: 2019-11-13)
Primary citationBell, M.J.,Brooks, A.G.,Burrows, S.R.,Clements, C.S.,Gras, S.,Kjer-Nielsen, L.,Liu, Y.C.,McCluskey, J.,Purcell, A.W.,Rossjohn, J.,Sullivan, L.C.
The shaping of T cell receptor recognition by self-tolerance.
Immunity, 30:193-203, 2009
PubMed: 19167249
DOI: 110.1016/j.immuni.2008.11.011
PDB entries with the same primary citation
Experimental method
Structure validation
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PDB entries from 2021-06-23