7BBF
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6K2U
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![BU of 6k2u by Molmil](/molmil-images/mine/6k2u) | Crystal structure of Thr66 ADP-ribosylated ubiquitin | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, MAGNESIUM ION, Polyubiquitin-C, ... | 著者 | Wang, X, Zhou, Y, Zhu, Y. | 登録日 | 2019-05-15 | 公開日 | 2020-03-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.554 Å) | 主引用文献 | Threonine ADP-Ribosylation of Ubiquitin by a Bacterial Effector Family Blocks Host Ubiquitination. Mol.Cell, 78, 2020
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7XCR
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![BU of 7xcr by Molmil](/molmil-images/mine/7xcr) | Cryo-EM structure of Dot1L and H2BK34ub-H3K79Nle nucleosome 1:1 complex | 分子名称: | DNA (146-MER), Histone H2A, Histone H2B type 1-K, ... | 著者 | Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L. | 登録日 | 2022-03-25 | 公開日 | 2022-04-20 | 最終更新日 | 2022-09-07 | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | 主引用文献 | H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity. Nat.Chem.Biol., 18, 2022
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6T7F
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![BU of 6t7f by Molmil](/molmil-images/mine/6t7f) | RCR E3 ligase E2-Ubiquitin transthiolation intermediate | 分子名称: | 3,3-bis(sulfanyl)-~{N}-(1~{H}-1,2,3-triazol-4-ylmethyl)propanamide, E3 ubiquitin-protein ligase MYCBP2, Polyubiquitin-C, ... | 著者 | Mabbitt, P.D, Virdee, S. | 登録日 | 2019-10-21 | 公開日 | 2020-08-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity. Nat.Chem.Biol., 16, 2020
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5H07
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![BU of 5h07 by Molmil](/molmil-images/mine/5h07) | TNIP2-Ub complex, C2 form | 分子名称: | Polyubiquitin-C, TNFAIP3-interacting protein 2 | 著者 | Lo, Y.C, Lin, S.C. | 登録日 | 2016-10-04 | 公開日 | 2017-03-08 | 実験手法 | X-RAY DIFFRACTION (2.586 Å) | 主引用文献 | Structural Insights into Linear Tri-ubiquitin Recognition by A20-Binding Inhibitor of NF-kappa B, ABIN-2 Structure, 25, 2017
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7YUI
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3N3K
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![BU of 3n3k by Molmil](/molmil-images/mine/3n3k) | The catalytic domain of USP8 in complex with a USP8 specific inhibitor | 分子名称: | Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 8, ZINC ION | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Allali-Hassani, A, Lam, R, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium, Structural Genomics Consortium (SGC) | 登録日 | 2010-05-20 | 公開日 | 2010-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A strategy for modulation of enzymes in the ubiquitin system. Science, 339, 2013
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6A6I
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![BU of 6a6i by Molmil](/molmil-images/mine/6a6i) | Crystal structure of the winged-helix domain of Cockayne syndrome group B protein in complex with ubiquitin | 分子名称: | CHLORIDE ION, Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant, ... | 著者 | Takahashi, T.S, Sato, Y, Fukai, S. | 登録日 | 2018-06-28 | 公開日 | 2019-02-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis of ubiquitin recognition by the winged-helix domain of Cockayne syndrome group B protein. Nucleic Acids Res., 47, 2019
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5N38
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![BU of 5n38 by Molmil](/molmil-images/mine/5n38) | S65DParkin and pUB complex | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, ... | 著者 | Kumar, A, Chaugule, V.K, Johnson, C, Toth, R, Sundaramoorthy, R, Knebel, A, Walden, H. | 登録日 | 2017-02-08 | 公開日 | 2017-04-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity. Nat. Struct. Mol. Biol., 24, 2017
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3DVG
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2OJR
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3LDZ
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5TUT
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4MDK
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![BU of 4mdk by Molmil](/molmil-images/mine/4mdk) | Cdc34-ubiquitin-CC0651 complex | 分子名称: | 4,5-dideoxy-5-(3',5'-dichlorobiphenyl-4-yl)-4-[(methoxyacetyl)amino]-L-arabinonic acid, Ubiquitin, Ubiquitin-conjugating enzyme E2 R1 | 著者 | Ceccarelli, D.F, Orlicky, S, Tyers, M, Sicheri, F. | 登録日 | 2013-08-22 | 公開日 | 2013-12-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6095 Å) | 主引用文献 | E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin. Nat.Chem.Biol., 10, 2014
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6BYH
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5CAW
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![BU of 5caw by Molmil](/molmil-images/mine/5caw) | |
6WTG
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![BU of 6wtg by Molmil](/molmil-images/mine/6wtg) | SdeA DUB Domain in complex with Ubiquitin | 分子名称: | Ubiquitin, Ubiquitinating/deubiquitinating enzyme SdeA | 著者 | Kenny, S, Sheedlo, M, Das, C. | 登録日 | 2020-05-02 | 公開日 | 2021-03-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Insights into Ubiquitin Product Release in Hydrolysis Catalyzed by the Bacterial Deubiquitinase SdeA. Biochemistry, 60, 2021
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7W54
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5CRA
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![BU of 5cra by Molmil](/molmil-images/mine/5cra) | Structure of the SdeA DUB Domain | 分子名称: | METHYL 4-AMINOBUTANOATE, Polyubiquitin-B, SULFATE ION, ... | 著者 | Sheedlo, M.J, Qiu, J, Luo, Z.Q, Das, C. | 登録日 | 2015-07-22 | 公開日 | 2015-11-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Structural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitination. Proc.Natl.Acad.Sci.USA, 112, 2015
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5D0K
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![BU of 5d0k by Molmil](/molmil-images/mine/5d0k) | Structure of UbE2D2:RNF165:Ub complex | 分子名称: | Polyubiquitin-B, RING finger protein 165, Ubiquitin-conjugating enzyme E2 D2, ... | 著者 | Wright, J.D, Day, C.L, Mace, P.D. | 登録日 | 2015-08-03 | 公開日 | 2015-12-09 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity. Nat.Struct.Mol.Biol., 23, 2016
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6Z7V
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![BU of 6z7v by Molmil](/molmil-images/mine/6z7v) | Crystal structure of Mindy2 (C266A) in complex with Lys48 linked di-ubiquitin (K48-Ub2) | 分子名称: | POTASSIUM ION, Polyubiquitin-C, TETRAETHYLENE GLYCOL, ... | 著者 | Abdul Rehman, S.A, Lange, S.M, Kulathu, Y. | 登録日 | 2020-06-01 | 公開日 | 2021-06-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2. Mol.Cell, 81, 2021
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6BVA
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5N2W
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![BU of 5n2w by Molmil](/molmil-images/mine/5n2w) | WT-Parkin and pUB complex | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ... | 著者 | Kumar, A, Chaugule, V.K, Johnson, C, Toth, R, Sundaramoorthy, R, Knebel, A, Walden, H. | 登録日 | 2017-02-08 | 公開日 | 2017-04-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity. Nat. Struct. Mol. Biol., 24, 2017
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5B83
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3MTN
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![BU of 3mtn by Molmil](/molmil-images/mine/3mtn) | Usp21 in complex with a ubiquitin-based, USP21-specific inhibitor | 分子名称: | CHLORIDE ION, GLYCEROL, UBIQUITIN VARIANT UBV.21.4, ... | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2010-04-30 | 公開日 | 2010-06-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A strategy for modulation of enzymes in the ubiquitin system. Science, 339, 2013
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