5B83
Crystal structure of Optineurin UBAN in complex with linear ubiquitin
Summary for 5B83
| Entry DOI | 10.2210/pdb5b83/pdb |
| Descriptor | tetra ubiquitin, Optineurin (3 entities in total) |
| Functional Keywords | ubiquitin, coiled-coil, cellular, signaling, nfkb pathway, signaling protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 6 |
| Total formula weight | 114971.48 |
| Authors | Ishii, R.,Nureki, O. (deposition date: 2016-06-12, release date: 2016-09-07, Last modification date: 2023-11-08) |
| Primary citation | Nakazawa, S.,Oikawa, D.,Ishii, R.,Ayaki, T.,Takahashi, H.,Takeda, H.,Ishitani, R.,Kamei, K.,Takeyoshi, I.,Kawakami, H.,Iwai, K.,Hatada, I.,Sawasaki, T.,Ito, H.,Nureki, O.,Tokunaga, F. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis Nat Commun, 7:12547-12547, 2016 Cited by PubMed: 27552911DOI: 10.1038/ncomms12547 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.694 Å) |
Structure validation
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