5HOB
 
 | | p73 homo-tetramerization domain mutant I | | 分子名称: | MAGNESIUM ION, Tumor protein p73 | | 著者 | Coutandin, D, Krojer, T, Salah, E, Mathea, S, Knapp, S, Dotsch, V. | | 登録日 | 2016-01-19 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.220013 Å) | | 主引用文献 | Structural basis of p63/p73 hetero-tetramerization
To Be Published
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5HOC
 | | p73 homo-tetramerization domain mutant II | | 分子名称: | Tumor protein p73 | | 著者 | Coutandin, D, Krojer, T, Salah, E, Mathea, S, Sumyk, M, Knapp, S, Dotsch, V. | | 登録日 | 2016-01-19 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.36007786 Å) | | 主引用文献 | Mechanism of TAp73 inhibition by Delta Np63 and structural basis of p63/p73 hetero-tetramerization.
Cell Death Differ., 23, 2016
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2WQI
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8P9C
 | | Crystal structure of p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 F11 | | 分子名称: | 1,2-ETHANEDIOL, Darpin 1810 F11, Tumor protein 63, ... | | 著者 | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2023-06-05 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma.
Cell Death Dis, 14, 2023
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2XWC
 | | Crystal structure of the DNA binding domain of human TP73 refined at 1.8 A resolution | | 分子名称: | GLYCEROL, TRIS(HYDROXYETHYL)AMINOMETHANE, TUMOUR PROTEIN P73, ... | | 著者 | Canning, P, Zhang, Y, Vollmar, M, Krojer, T, Ugochukwu, E, Muniz, J.R.C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N. | | 登録日 | 2010-11-03 | | 公開日 | 2010-11-17 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structural Basis for Aspp2 Recognition by the Tumor Suppressor P73.
J.Mol.Biol., 423, 2012
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2WQJ
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8P9E
 | | Crystal structure of wild type p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 F11 | | 分子名称: | Darpin 1810 F11, GLYCEROL, Isoform 2 of Tumor protein 63, ... | | 著者 | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2023-06-05 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma.
Cell Death Dis, 14, 2023
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4A63
 | | Crystal structure of the p73-ASPP2 complex at 2.6A resolution | | 分子名称: | ACETATE ION, APOPTOSIS STIMULATING OF P53 PROTEIN 2, TUMOUR PROTEIN 73, ... | | 著者 | Canning, P, Sharpe, T, Krojer, T, Savitsky, P, Cooper, C.D.O, Salah, E, Keates, T, Muniz, J, Vollmar, M, von Delft, F, Weigelt, J, Arrowsmith, C, Bountra, C, Edwards, A, Bullock, A.N. | | 登録日 | 2011-10-31 | | 公開日 | 2011-12-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Structural Basis for Aspp2 Recognition by the Tumor Suppressor P73.
J.Mol.Biol., 423, 2012
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2WTT
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1DXS
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8P9D
 | | Crystal structure of p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 A2 | | 分子名称: | Darpin 1810 A2, Tumor protein 63, Tumor protein p73 | | 著者 | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2023-06-05 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma.
Cell Death Dis, 14, 2023
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5KBD
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7EZJ
 | | Crystal structure of p73 DNA binding domain complex bound with 1 bp and 2 bp spacer DNA response elements. | | 分子名称: | 12-mer DNA, Tumor protein p73, ZINC ION | | 著者 | Koley, T, Roy Chowdhury, S, Kumar, M, Kaur, P, Singh, T.P, Viadiu, H, Ethayathulla, A.S. | | 登録日 | 2021-06-01 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Deciphering the mechanism of p73 recognition of p53 response elements using the crystal structure of p73-DNA complexes and computational studies.
Int.J.Biol.Macromol., 206, 2022
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3VD1
 | | structure of p73 DNA binding domain tetramer modulates p73 transactivation | | 分子名称: | DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), Tumor protein p73, ZINC ION | | 著者 | Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H. | | 登録日 | 2012-01-04 | | 公開日 | 2012-04-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structure of p73 DNA-binding domain tetramer modulates p73 transactivation.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3VD0
 | | structure of p73 DNA binding domain tetramer modulates p73 transactivation | | 分子名称: | DNA (5'-D(*CP*AP*GP*GP*CP*AP*TP*GP*CP*CP*TP*G)-3'), Tumor protein p73, ZINC ION | | 著者 | Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H. | | 登録日 | 2012-01-04 | | 公開日 | 2012-04-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structure of p73 DNA-binding domain tetramer modulates p73 transactivation.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4G82
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4GUO
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4GUQ
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4G83
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3VD2
 | | structure of p73 DNA binding domain tetramer modulates p73 transactivation | | 分子名称: | DNA (5'-D(*AP*TP*GP*GP*AP*CP*AP*TP*GP*TP*CP*CP*AP*T)-3'), Tumor protein p73, ZINC ION | | 著者 | Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H. | | 登録日 | 2012-01-04 | | 公開日 | 2012-04-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Structure of p73 DNA-binding domain tetramer modulates p73 transactivation.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2KBY
 | | The Tetramerization Domain of Human p73 | | 分子名称: | Tumor protein p73 | | 著者 | Coutandin, D, Ikeya, T, Loehr, F, Guntert, P, Ou, H.D, Doetsch, V. | | 登録日 | 2008-12-12 | | 公開日 | 2009-09-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Conformational stability and activity of p73 require a second helix in the tetramerization domain.
Cell Death Differ., 16, 2009
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6IJQ
 | | Solution structure of BCL-XL bound to P73-TAD peptide | | 分子名称: | Bcl-2-like protein 1,Bcl-2-like protein 1, Tumor protein p73 | | 著者 | Yoon, M.-K, Ha, J.-H, Lee, M.-S, Chi, S.-W. | | 登録日 | 2018-10-11 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Cytoplasmic pro-apoptotic function of the tumor suppressor p73 is mediated through a modified mode of recognition of the anti-apoptotic regulator Bcl-XL.
J. Biol. Chem., 293, 2018
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6FGS
 | | Solution structure of p300Taz2-p73TA1 | | 分子名称: | Histone acetyltransferase p300,Tumor protein p73, ZINC ION | | 著者 | Gebel, J, Kazemi, S, Lohr, F, Guntert, P, Dotsch, V. | | 登録日 | 2018-01-11 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain.
Structure, 26, 2018
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2NB1
 | | P63/p73 hetero-tetramerisation domain | | 分子名称: | Tumor protein 63, Tumor protein p73 | | 著者 | Gebel, J, Buchner, L, Loehr, F.M, Luh, L.M, Coutandin, D, Guentert, P, Doetsch, V. | | 登録日 | 2016-01-19 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mechanism of TAp73 inhibition by Delta Np63 and structural basis of p63/p73 hetero-tetramerization.
Cell Death Differ., 23, 2016
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1COK
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