7EZJ

Crystal structure of p73 DNA binding domain complex bound with 1 bp and 2 bp spacer DNA response elements.

Summary for 7EZJ

Entry DOI	10.2210/pdb7ezj/pdb
Descriptor	Tumor protein p73, 12-mer DNA, ZINC ION, ... (4 entities in total)
Functional Keywords	dna binding protein, dna binding protein-dna complex, dna binding protein/dna
Biological source	Homo sapiens (Human) More
Total number of polymer chains	32
Total formula weight	440076.10
Authors	Koley, T.,Roy Chowdhury, S.,Kumar, M.,Kaur, P.,Singh, T.P.,Viadiu, H.,Ethayathulla, A.S. (deposition date: 2021-06-01, release date: 2022-04-13, Last modification date: 2023-11-29)
Primary citation	Koley, T.,Roy Chowdhury, S.,Kushwaha, T.,Kumar, M.,Inampudi, K.K.,Kaur, P.,Singh, T.P.,Viadiu, H.,Ethayathulla, A.S. Deciphering the mechanism of p73 recognition of p53 response elements using the crystal structure of p73-DNA complexes and computational studies. Int.J.Biol.Macromol., 206:40-50, 2022 Cited by PubMed: 35217090 DOI: 10.1016/j.ijbiomac.2022.02.108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation