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7EZJ

Crystal structure of p73 DNA binding domain complex bound with 1 bp and 2 bp spacer DNA response elements.

Functional Information from GO Data
ChainGOidnamespacecontents
a0000976molecular_functiontranscription cis-regulatory region binding
a0003677molecular_functionDNA binding
a0003700molecular_functionDNA-binding transcription factor activity
a0005634cellular_componentnucleus
a0006355biological_processregulation of DNA-templated transcription
a0006915biological_processapoptotic process
A0000976molecular_functiontranscription cis-regulatory region binding
A0003677molecular_functionDNA binding
A0003700molecular_functionDNA-binding transcription factor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
A0006915biological_processapoptotic process
b0000976molecular_functiontranscription cis-regulatory region binding
b0003677molecular_functionDNA binding
b0003700molecular_functionDNA-binding transcription factor activity
b0005634cellular_componentnucleus
b0006355biological_processregulation of DNA-templated transcription
b0006915biological_processapoptotic process
B0000976molecular_functiontranscription cis-regulatory region binding
B0003677molecular_functionDNA binding
B0003700molecular_functionDNA-binding transcription factor activity
B0005634cellular_componentnucleus
B0006355biological_processregulation of DNA-templated transcription
B0006915biological_processapoptotic process
c0000976molecular_functiontranscription cis-regulatory region binding
c0003677molecular_functionDNA binding
c0003700molecular_functionDNA-binding transcription factor activity
c0005634cellular_componentnucleus
c0006355biological_processregulation of DNA-templated transcription
c0006915biological_processapoptotic process
C0000976molecular_functiontranscription cis-regulatory region binding
C0003677molecular_functionDNA binding
C0003700molecular_functionDNA-binding transcription factor activity
C0005634cellular_componentnucleus
C0006355biological_processregulation of DNA-templated transcription
C0006915biological_processapoptotic process
d0000976molecular_functiontranscription cis-regulatory region binding
d0003677molecular_functionDNA binding
d0003700molecular_functionDNA-binding transcription factor activity
d0005634cellular_componentnucleus
d0006355biological_processregulation of DNA-templated transcription
d0006915biological_processapoptotic process
D0000976molecular_functiontranscription cis-regulatory region binding
D0003677molecular_functionDNA binding
D0003700molecular_functionDNA-binding transcription factor activity
D0005634cellular_componentnucleus
D0006355biological_processregulation of DNA-templated transcription
D0006915biological_processapoptotic process
i0000976molecular_functiontranscription cis-regulatory region binding
i0003677molecular_functionDNA binding
i0003700molecular_functionDNA-binding transcription factor activity
i0005634cellular_componentnucleus
i0006355biological_processregulation of DNA-templated transcription
i0006915biological_processapoptotic process
I0000976molecular_functiontranscription cis-regulatory region binding
I0003677molecular_functionDNA binding
I0003700molecular_functionDNA-binding transcription factor activity
I0005634cellular_componentnucleus
I0006355biological_processregulation of DNA-templated transcription
I0006915biological_processapoptotic process
j0000976molecular_functiontranscription cis-regulatory region binding
j0003677molecular_functionDNA binding
j0003700molecular_functionDNA-binding transcription factor activity
j0005634cellular_componentnucleus
j0006355biological_processregulation of DNA-templated transcription
j0006915biological_processapoptotic process
J0000976molecular_functiontranscription cis-regulatory region binding
J0003677molecular_functionDNA binding
J0003700molecular_functionDNA-binding transcription factor activity
J0005634cellular_componentnucleus
J0006355biological_processregulation of DNA-templated transcription
J0006915biological_processapoptotic process
k0000976molecular_functiontranscription cis-regulatory region binding
k0003677molecular_functionDNA binding
k0003700molecular_functionDNA-binding transcription factor activity
k0005634cellular_componentnucleus
k0006355biological_processregulation of DNA-templated transcription
k0006915biological_processapoptotic process
K0000976molecular_functiontranscription cis-regulatory region binding
K0003677molecular_functionDNA binding
K0003700molecular_functionDNA-binding transcription factor activity
K0005634cellular_componentnucleus
K0006355biological_processregulation of DNA-templated transcription
K0006915biological_processapoptotic process
l0000976molecular_functiontranscription cis-regulatory region binding
l0003677molecular_functionDNA binding
l0003700molecular_functionDNA-binding transcription factor activity
l0005634cellular_componentnucleus
l0006355biological_processregulation of DNA-templated transcription
l0006915biological_processapoptotic process
L0000976molecular_functiontranscription cis-regulatory region binding
L0003677molecular_functionDNA binding
L0003700molecular_functionDNA-binding transcription factor activity
L0005634cellular_componentnucleus
L0006355biological_processregulation of DNA-templated transcription
L0006915biological_processapoptotic process
Functional Information from PROSITE/UniProt
site_idPS00348
Number of Residues13
DetailsP53 p53 family signature. MCNSSCVGGMNRR
ChainResidueDetails
AMET257-ARG269

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2864
DetailsRegion: {"description":"DNA-binding","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues64
DetailsBinding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

255615

PDB entries from 2026-06-24

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