2WTT
Structure of the human p73 tetramerization domain (crystal form II)
Summary for 2WTT
| Entry DOI | 10.2210/pdb2wtt/pdb |
| Related | 1COK 1DXS 2WQI |
| Descriptor | TUMOR PROTEIN P73 (2 entities in total) |
| Functional Keywords | alternative splicing, oligomerization domain, cell-cycle control, transcription factor, cooperativity, phosphoprotein, ubl conjugation, activator, tumor suppression, development, transcription, apoptosis, cell cycle, dna binding, transcription regulation |
| Biological source | HOMO SAPIENS (HUMAN) |
| Total number of polymer chains | 16 |
| Total formula weight | 99611.71 |
| Authors | Joerger, A.C. (deposition date: 2009-09-21, release date: 2009-10-13, Last modification date: 2023-12-20) |
| Primary citation | Joerger, A.C.,Rajagopalan, S.,Natan, E.,Veprintsev, D.B.,Robinson, C.V.,Fersht, A.R. Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation. Proc.Natl.Acad.Sci.USA, 106:17705-, 2009 Cited by PubMed: 19815500DOI: 10.1073/PNAS.0905867106 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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