4GUQ

Structure of mutS139F p73 DNA binding domain complexed with 20BP DNA response element

Summary for 4GUQ

• Entry DOI: 10.2210/pdb4guq/pdb
• Related: 4g82 4g83
• Descriptor: DNA (5'-D(P*GP*AP*AP*CP*AP*TP*GP*TP*TP*C)-3'), Tumor protein p73, ZINC ION (3 entities in total)
• Functional Keywords: tumor suppressor, beta-immunoglobulin, transcription factor, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: O15350
• Total number of polymer chains: 4
• Total formula weight: 53890.95

Authors

Ethayathulla, A.S.,Nguyen, H.T.,Viadiu, H. (deposition date: 2012-08-29, release date: 2013-08-14, Last modification date: 2023-09-13)

• Primary citation: Ciribilli, Y.,Monti, P.,Bisio, A.,Nguyen, H.T.,Ethayathulla, A.S.,Ramos, A.,Foggetti, G.,Menichini, P.,Menendez, D.,Resnick, M.A.,Viadiu, H.,Fronza, G.,Inga, A.; Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code.; Nucleic Acids Res., 41:8637-8653, 2013; PubMed: 23892287; DOI: 10.1093/nar/gkt657

Experimental method

X-RAY DIFFRACTION (3.7 Å)