4GUQ

Structure of mutS139F p73 DNA binding domain complexed with 20BP DNA response element

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	E, F	DNA (5'-D(P*GP*AP*AP*CP*AP*TP*GP*TP*TP*C)-3')	polymer	10	3044.0	2
2	A, B	Tumor protein p73	polymer	210	23836.1	2	UniProt (O15350) Pfam (PF00870) In PDB	Homo sapiens (human)	p53-like transcription factor, p53-related protein
3	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

A, B: 115 - 312 (UniProt: O15350)

PDB	External Database	Details
Met 103	-	initiating methionine
Gly 104	-	expression tag
His 105	-	expression tag
His 106	-	expression tag
His 107	-	expression tag
His 108	-	expression tag
His 109	-	expression tag
His 110	-	expression tag
His 111	-	expression tag
His 112	-	expression tag
Glu 113	-	expression tag
Phe 114	-	expression tag
Phe 139	Ser 139	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	53760.1
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	53891.0

*Water molecules are not included.