6IJQ

Solution structure of BCL-XL bound to P73-TAD peptide

Summary for 6IJQ

DescriptorTumor protein p73, Bcl-2-like protein 1,Bcl-2-like protein 1 (2 entities in total)
Functional Keywordscomplex structure, apoptosis
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight22596.76
Authors
Yoon, M.-K.,Ha, J.-H.,Lee, M.-S.,Chi, S.-W. (deposition date: 2018-10-11, release date: 2018-11-21, Last modification date: 2019-01-02)
Primary citation
Yoon, M.-K.,Kim, B.-Y.,Lee, J.-Y.,Ha, J.-H.,Kim, S.A.,Lee, D.-H.,Lee, M.-S.,Lee, M.-K.,Choi, J.S.,Cho, J.H.,Kim, J.-H.,Kim, S.,Song, J.,Park, S.G.,Park, B.C.,Bae, K.-H.,Choi, S.U.,Chi, S.-W.
Cytoplasmic pro-apoptotic function of the tumor suppressor p73 is mediated through a modified mode of recognition of the anti-apoptotic regulator Bcl-XL.
J. Biol. Chem., 293:19546-19558, 2018
PubMed: 30429221 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.RA118.003061
MImport into Mendeley
Experimental method
SOLUTION NMR
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Structure validation

ClashscoreRamachandran outliersSidechain outliers3 1.7% 3.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures