2NB1

P63/p73 hetero-tetramerisation domain

Summary for 2NB1

• Entry DOI: 10.2210/pdb2nb1/pdb
• Related: 2KBY 4A9Z 5HOB 5HOC
• NMR Information: BMRB: 25958
• Descriptor: Tumor protein 63, Tumor protein p73 (2 entities in total)
• Functional Keywords: p63, p73, tetramerization domain, hetero tetramer, transcription factor, transcription
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : Q9H3D4 O15350
• Total number of polymer chains: 4
• Total formula weight: 26716.17

Authors

Gebel, J.,Buchner, L.,Loehr, F.M.,Luh, L.M.,Coutandin, D.,Guentert, P.,Doetsch, V. (deposition date: 2016-01-19, release date: 2016-12-07, Last modification date: 2023-06-14)

• Primary citation: Gebel, J.,Luh, L.M.,Coutandin, D.,Osterburg, C.,Lohr, F.,Schafer, B.,Frombach, A.S.,Sumyk, M.,Buchner, L.,Krojer, T.,Salah, E.,Mathea, S.,Guntert, P.,Knapp, S.,Dotsch, V.; Mechanism of TAp73 inhibition by Delta Np63 and structural basis of p63/p73 hetero-tetramerization.; Cell Death Differ., 23:1930-1940, 2016; PubMed: 27716744; DOI: 10.1038/cdd.2016.83

Experimental method

SOLUTION NMR