2NB1

P63/p73 hetero-tetramerisation domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Tumor protein 63	polymer	60	7323.2	2	UniProt (Q9H3D4) Pfam (PF07710)	Homo sapiens (human)	p63, Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, Transformation-related protein 63, TP63, Tumor protein p73-like, p73L, p40, p51
2	B, D (B, D)	Tumor protein p73	polymer	50	6034.9	2	UniProt (O15350) Pfam (PF07710)	Homo sapiens (human)	p53-like transcription factor, p53-related protein

Sequence modifications

A, C: 2 - 60 (UniProt: Q9H3D4)

PDB	External Database	Details
Ser 1	-	expression tag
Glu 21	Lys 416	engineered mutation

B, D: 95 - 142 (UniProt: O15350)

PDB	External Database	Details
Gly 93	-	expression tag
Ser 94	-	expression tag
Lys 107	Glu 363	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	26716.2
All*	Total formula weight	26716.2

*Water molecules are not included.