5HOC
p73 homo-tetramerization domain mutant II
Summary for 5HOC
Entry DOI | 10.2210/pdb5hoc/pdb |
Related | 2KBY 2NB1 4A9Z 5HOB |
Descriptor | Tumor protein p73 (2 entities in total) |
Functional Keywords | transcription factor, tetramerization domain, p73, homo-tetramerization mutant, hetero-tetramerization, transcription |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : O15350 |
Total number of polymer chains | 2 |
Total formula weight | 12097.63 |
Authors | Coutandin, D.,Krojer, T.,Salah, E.,Mathea, S.,Sumyk, M.,Knapp, S.,Dotsch, V. (deposition date: 2016-01-19, release date: 2016-10-19, Last modification date: 2024-01-10) |
Primary citation | Gebel, J.,Luh, L.M.,Coutandin, D.,Osterburg, C.,Lohr, F.,Schafer, B.,Frombach, A.S.,Sumyk, M.,Buchner, L.,Krojer, T.,Salah, E.,Mathea, S.,Guntert, P.,Knapp, S.,Dotsch, V. Mechanism of TAp73 inhibition by Delta Np63 and structural basis of p63/p73 hetero-tetramerization. Cell Death Differ., 23:1930-1940, 2016 Cited by PubMed: 27716744DOI: 10.1038/cdd.2016.83 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.36007789334 Å) |
Structure validation
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