4A63

Crystal structure of the p73-ASPP2 complex at 2.6A resolution

Summary for 4A63

Entry DOI	10.2210/pdb4a63/pdb
Related	1COK 1DXS 1YCS 2UWQ 2WQI 2WQJ 2WTT 2XWC
Descriptor	TUMOUR PROTEIN 73, APOPTOSIS STIMULATING OF P53 PROTEIN 2, ZINC ION, ... (5 entities in total)
Functional Keywords	cell cycle, tp53bp2, tumour suppressor, ankyrins, apoptosis regulatory proteins
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Nucleus : O15350 Cytoplasm, perinuclear region: Q13625
Total number of polymer chains	12
Total formula weight	302622.66
Authors	Canning, P.,Sharpe, T.,Krojer, T.,Savitsky, P.,Cooper, C.D.O.,Salah, E.,Keates, T.,Muniz, J.,Vollmar, M.,von Delft, F.,Weigelt, J.,Arrowsmith, C.,Bountra, C.,Edwards, A.,Bullock, A.N. (deposition date: 2011-10-31, release date: 2011-12-21, Last modification date: 2023-12-20)
Primary citation	Canning, P.,von Delft, F.,Bullock, A.N. Structural Basis for Aspp2 Recognition by the Tumor Suppressor P73. J.Mol.Biol., 423:515-, 2012 Cited by PubMed: 22917970 DOI: 10.1016/J.JMB.2012.08.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.27 Å)

Structure validation