2WQJ
Crystal structure of a truncated variant of the human p73 tetramerization domain
Summary for 2WQJ
| Entry DOI | 10.2210/pdb2wqj/pdb |
| Related | 1COK 1DXS 2WQI 2WTT |
| Descriptor | TUMOR PROTEIN P73 (2 entities in total) |
| Functional Keywords | p73, p63, p53, tumor suppression, transcription factor, tetramer, hexamer, oligomerization domain, dna-binding, cooperativity, transcription, cell-cycle control, transcription regulation, apoptosis, cell cycle, development |
| Biological source | HOMO SAPIENS (HUMAN) |
| Total number of polymer chains | 28 |
| Total formula weight | 117004.66 |
| Authors | Joerger, A.C. (deposition date: 2009-08-21, release date: 2009-10-06, Last modification date: 2019-05-08) |
| Primary citation | Joerger, A.C.,Rajagopalan, S.,Natan, E.,Veprintsev, D.B.,Robinson, C.V.,Fersht, A.R. Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation. Proc.Natl.Acad.Sci.USA, 106:17705-, 2009 Cited by PubMed: 19815500DOI: 10.1073/PNAS.0905867106 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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