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PDB: 74 件

5KQR
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Structure of NS5 methyltransferase from Zika virus bound to S-adenosylmethionine
分子名称: CHLORIDE ION, Methyltransferase, PHOSPHATE ION, ...
著者Jain, R, Coloma, J, Rajashankar, K.R, Aggarwal, A.K.
登録日2016-07-06
公開日2016-09-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.331 Å)
主引用文献Structures of NS5 Methyltransferase from Zika Virus.
Cell Rep, 16, 2016
6LD2
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Zika NS5 polymerase domain
分子名称: (1S,2S,4S,5R)-2,4-dimethoxy-5-thiophen-2-yl-cyclohexane-1-carboxylic acid, RNA-directed RNA polymerase NS5, ZINC ION
著者El Sahili, A, Lescar, J.
登録日2019-11-20
公開日2020-08-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase.
J.Virol., 94, 2020
6LD1
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Zika NS5 polymerase domain
分子名称: 1,2-ETHANEDIOL, RNA-directed RNA polymerase NS5, ZINC ION
著者El Sahili, A, Lescar, J.
登録日2019-11-20
公開日2020-08-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase.
J.Virol., 94, 2020
5KVG
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Zika specific antibody, ZV-67, bound to ZIKA envelope DIII
分子名称: CHLORIDE ION, ZIKA Envelope DIII, ZV-67 Antibody Fab Heavy Chain, ...
著者Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-07-14
公開日2016-08-03
最終更新日2016-08-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural Basis of Zika Virus-Specific Antibody Protection.
Cell, 166, 2016
5KVF
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Zika specific antibody, ZV-64, bound to ZIKA envelope DIII
分子名称: GLYCEROL, ZV-64 Antibody Fab Heavy Chain, ZV-64 Antibody Fab Light Chain, ...
著者Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-07-14
公開日2016-08-03
最終更新日2016-08-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural Basis of Zika Virus-Specific Antibody Protection.
Cell, 166, 2016
5KQS
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Structure of NS5 methyltransferase from Zika virus bound to S-adenosylmethionine and 7-methyl-guanosine-5'-diphosphate
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, ACETATE ION, GLYCEROL, ...
著者Coloma, J, Jain, R, Rajashankar, K.R, Aggarwal, A.K.
登録日2016-07-06
公開日2016-09-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structures of NS5 Methyltransferase from Zika Virus.
Cell Rep, 16, 2016
6LD4
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Zika NS5 polymerase domain
分子名称: 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid, 3-methoxybenzenesulfonamide, RNA-directed RNA polymerase NS5, ...
著者El Sahili, A, Lescar, J.
登録日2019-11-20
公開日2020-08-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase.
J.Virol., 94, 2020
6S0J
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Structure of Zika virus NS3 helicase in complex with ADP-MgF3(H2O)-
分子名称: ADENOSINE-5'-DIPHOSPHATE, Genome polyprotein, MAGNESIUM ION, ...
著者Ge, M, Molt Jr, R.W, Jenkins, H.T, Blackburn, G.M, Jin, Y, Antson, A.A.
登録日2019-06-16
公開日2020-07-15
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Octahedral Trifluoromagnesate, an Anomalous Metal Fluoride Species, Stabilizes the Transition State in a Biological Motor.
Acs Catalysis, 11, 2021
5ULP
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Structure of the NS5 methyltransferase from Zika bound to MS2042
分子名称: 5'-{[(3S)-3-amino-3-carboxypropyl][(4-fluorophenyl)methyl]amino}-5'-deoxyadenosine, CHLORIDE ION, ISOPROPYL ALCOHOL, ...
著者Jain, R, Aggarwal, A.K.
登録日2017-01-25
公開日2017-05-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Development of a S-adenosylmethionine analog that intrudes the RNA-cap binding site of Zika methyltransferase.
Sci Rep, 7, 2017
5Y6N
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Zika virus helicase in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Helicase domain from Genome polyprotein, MANGANESE (II) ION
著者Yang, X.Y, Chen, C, Tian, H.L, Chi, H, Mu, Z.Y, Zhang, T.Q, Yang, K.L, Zhao, Q, Liu, X.H, Wang, Z.F, Ji, X.Y, Yang, H.T.
登録日2017-08-12
公開日2018-07-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.571 Å)
主引用文献Mechanism of ATP hydrolysis by the Zika virus helicase.
FASEB J., 32, 2018
7M1V
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Structure of Zika virus NS2b-NS3 protease mutant binding the compound NSC86314 in the super-open conformation
分子名称: 1,2-ETHANEDIOL, 4-(2-{2,4-diamino-5-[2-(4-{[(2E)-1,3-thiazolidin-2-ylidene]sulfamoyl}phenyl)hydrazinyl]phenyl}hydrazinyl)-N-[(2S)-1,3-thiazolidin-2-yl]benzene-1-sulfonamide, CHLORIDE ION, ...
著者Aleshin, A.E, Shiryaev, S.A, Liddington, R.C.
登録日2021-03-15
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献To be provided
To Be Published
5KVD
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BU of 5kvd by Molmil
Zika specific antibody, ZV-2, bound to ZIKA envelope DIII
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SODIUM ION, ...
著者Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-07-14
公開日2016-08-03
最終更新日2016-08-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Basis of Zika Virus-Specific Antibody Protection.
Cell, 166, 2016
5KVE
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BU of 5kve by Molmil
Zika specific antibody, ZV-48, bound to ZIKA envelope DIII
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Genome polyprotein, ...
著者Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-07-14
公開日2016-08-10
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis of Zika Virus-Specific Antibody Protection.
Cell, 166, 2016
6RWZ
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BU of 6rwz by Molmil
Structure of Zika virus NS3 helicase in complex with ADP-BeF3
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MANGANESE (II) ION, ...
著者Ge, M, Molt Jr, R.W, Jenkins, H.T, Blackburn, G.M, Jin, Y, Antson, A.A.
登録日2019-06-07
公開日2020-07-15
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Octahedral Trifluoromagnesate, an Anomalous Metal Fluoride Species, Stabilizes the Transition State in a Biological Motor.
Acs Catalysis, 11, 2021
5JMT
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BU of 5jmt by Molmil
Crystal structure of Zika virus NS3 helicase
分子名称: NS3 helicase
著者Tian, H, Ji, X, Yang, X, Xie, W, Yang, K, Chen, C, Wu, C, Chi, H, Mu, Z, Wang, Z, Yang, H.
登録日2016-04-29
公開日2016-05-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.796 Å)
主引用文献The crystal structure of Zika virus helicase: basis for antiviral drug design
Protein Cell, 7, 2016
5YGH
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BU of 5ygh by Molmil
Crystal Structure of the Capsid Protein from Zika Virus
分子名称: Capsid protein
著者Shang, Z, Song, H, Shi, Y, Qi, J, Gao, G.F.
登録日2017-09-23
公開日2018-02-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.884 Å)
主引用文献Crystal Structure of the Capsid Protein from Zika Virus.
J. Mol. Biol., 430, 2018
5MRK
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Structural basis of Zika virus methyltransferase inhibition by sinefungin
分子名称: CHLORIDE ION, SINEFUNGIN, methyltransferase
著者Hercik, K, Boura, E.
登録日2016-12-23
公開日2017-01-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of Zika virus methyltransferase inhibition by sinefungin.
Arch. Virol., 162, 2017
6LD5
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BU of 6ld5 by Molmil
Zika NS5 polymerase domain
分子名称: 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid, RNA-directed RNA polymerase NS5, ZINC ION, ...
著者El Sahili, A, Lescar, J.
登録日2019-11-20
公開日2020-08-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase.
J.Virol., 94, 2020
5JHM
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Crystal structure of Zika virus Envelope protein
分子名称: Envelope protein
著者Dai, L, Shi, Y, Qi, J, Gao, G.F.
登録日2016-04-21
公開日2016-05-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody.
Cell Host Microbe, 19, 2016
5NJV
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BU of 5njv by Molmil
Flavivirus NS5 domain
分子名称: CHLORIDE ION, NS5, S-ADENOSYLMETHIONINE
著者Talapatra, S.K, Chatrin, C, Kozielski, F.
登録日2017-03-29
公開日2018-01-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping.
Oncotarget, 9, 2018
5Y6M
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Zika virus helicase in complex with ADP-AlF3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Helicase domain from Genome polyprotein, ...
著者Yang, X.Y, Chen, C, Tian, H.L, Chi, H, Mu, Z.Y, Zhang, T.Q, Yang, K.L, Zhao, Q, Liu, X.H, Wang, Z.F, Ji, X.Y, Yang, H.T.
登録日2017-08-12
公開日2018-07-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Mechanism of ATP hydrolysis by the Zika virus helicase.
FASEB J., 32, 2018
5M5B
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BU of 5m5b by Molmil
Crystal structure of Zika virus NS5 methyltransferase
分子名称: CHLORIDE ION, GLYCEROL, NS5 methyltransferase, ...
著者Barral, K, Ortiz Lombardia, M, Coutard, B, Decroly, E, Lichiere, J.
登録日2016-10-21
公開日2016-12-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives.
J. Virol., 91, 2017
5GOZ
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Crystal structure of ZIKV NS5 Methyltransferase in complex with GTP and SAH
分子名称: GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, PYROPHOSPHATE 2-, ...
著者Zhang, C, Jin, T.
登録日2016-07-30
公開日2016-12-07
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.049 Å)
主引用文献Structure of the NS5 methyltransferase from Zika virus and implications in inhibitor design
Biochem. Biophys. Res. Commun., 492, 2017
5TXG
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Crystal structure of the Zika virus NS3 helicase.
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, NS3 helicase, POTASSIUM ION
著者Nocadello, S, Light, S.H, Minasov, G, Shuvalova, L, Cardona-Correa, A.A, Ojeda, I, Vargas, J, Johnson, M.E, Lee, H, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-11-16
公開日2016-12-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of the Zika virus NS3 helicase.
To be published
7A3N
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Crystal structure of Zika virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE1 C10
分子名称: CALCIUM ION, Core protein, EDE1 C10 Fab
著者Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Rey, F.A.
登録日2020-08-18
公開日2021-12-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021

 

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