3NNG
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![BU of 3nng by Molmil](/molmil-images/mine/3nng) | Crystal structure of the F5/8 type C domain of Q5LFR2_BACFN protein from Bacteroides fragilis. Northeast Structural Genomics Consortium Target BfR258E | Descriptor: | CALCIUM ION, uncharacterized protein | Authors: | Vorobiev, S, Su, M, Dimaio, F, Baker, D, Seetharaman, J, Janjua, J, Xiao, R, Ciccosanti, C, Foote, E.L, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-06-23 | Release date: | 2010-08-18 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.177 Å) | Cite: | Crystal structure of the F5/8 type C domain of Q5LFR2_BACFN protein from Bacteroides fragilis. To be Published
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5Y4M
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![BU of 5y4m by Molmil](/molmil-images/mine/5y4m) | Discoidin domain of human CASPR2 | Descriptor: | 1,2-ETHANEDIOL, human CASPR2 Disc domain | Authors: | Liu, H, Xu, F, Zhang, J, Liang, W. | Deposit date: | 2017-08-04 | Release date: | 2018-08-08 | Last modified: | 2019-02-20 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Structural mapping of hot spots within human CASPR2 discoidin domain for autoantibody recognition. J. Autoimmun., 96, 2019
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3JD6
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![BU of 3jd6 by Molmil](/molmil-images/mine/3jd6) | Double octamer structure of retinoschisin, a cell-cell adhesion protein of the retina | Descriptor: | Retinoschisin | Authors: | Tolun, G, Vijayasarathy, C, Huang, R, Zeng, Y, Li, Y, Steven, A.C, Sieving, P.A, Heymann, J.B. | Deposit date: | 2016-04-12 | Release date: | 2016-05-11 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Paired octamer rings of retinoschisin suggest a junctional model for cell-cell adhesion in the retina. Proc.Natl.Acad.Sci.USA, 113, 2016
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3BN6
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![BU of 3bn6 by Molmil](/molmil-images/mine/3bn6) | Crystal Structure of the C2 Domain of Bovine Lactadherin at 1.67 Angstrom Resolution | Descriptor: | Lactadherin | Authors: | Shao, C, Novakovic, V.A, Head, J.F, Seaton, B.A, Gilbert, G.E. | Deposit date: | 2007-12-13 | Release date: | 2007-12-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Crystal structure of lactadherin C2 domain at 1.7A resolution with mutational and computational analyses of its membrane-binding motif. J.Biol.Chem., 283, 2008
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4MO3
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![BU of 4mo3 by Molmil](/molmil-images/mine/4mo3) | |
6OE2
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![BU of 6oe2 by Molmil](/molmil-images/mine/6oe2) | |
5IJR
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![BU of 5ijr by Molmil](/molmil-images/mine/5ijr) | X-ray structure of neuropilin-1 b1 domain complexed with Arg-1 ligand. | Descriptor: | DIMETHYL SULFOXIDE, L-HOMOARGININE, Neuropilin-1 | Authors: | Fotinou, C, Rana, R, Djordjevic, S, Yelland, T. | Deposit date: | 2016-03-02 | Release date: | 2017-03-29 | Last modified: | 2018-07-11 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Architecture and hydration of the arginine-binding site of neuropilin-1. FEBS J., 285, 2018
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2JD9
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5IYY
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![BU of 5iyy by Molmil](/molmil-images/mine/5iyy) | X-ray structure of neuropilin-1 b1 domain complexed with Arg-4 ligand. | Descriptor: | Neuropilin-1, N~2~-[(benzyloxy)carbonyl]-L-arginine | Authors: | Fotinou, C, Rana, R, Djordjevic, S, Yelland, T. | Deposit date: | 2016-03-24 | Release date: | 2017-04-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Architecture and hydration of the arginine-binding site of neuropilin-1. FEBS J., 285, 2018
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6FMF
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![BU of 6fmf by Molmil](/molmil-images/mine/6fmf) | Neuropilin-1 b1 domain in complex with EG01377; 2.8 Angstrom structure | Descriptor: | (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, Neuropilin-1, trifluoroacetic acid | Authors: | Yelland, T, Djordjevic, S, Selwood, D, Zachary, I, Frankel, P. | Deposit date: | 2018-01-31 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.811 Å) | Cite: | Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells. J. Med. Chem., 61, 2018
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5JHK
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![BU of 5jhk by Molmil](/molmil-images/mine/5jhk) | X-ray structure of neuropilin-1 b1 domain complexed with Arg-6 ligand. | Descriptor: | N-(benzenecarbonyl)glycyl-L-arginine, Neuropilin-1 | Authors: | Fotinou, C, Rana, R, Djordjevic, S, Yelland, T. | Deposit date: | 2016-04-21 | Release date: | 2017-05-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Architecture and hydration of the arginine-binding site of neuropilin-1. FEBS J., 285, 2018
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6FMC
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![BU of 6fmc by Molmil](/molmil-images/mine/6fmc) | Neuropilin1-b1 domain in complex with EG01377, 0.9 Angstrom structure | Descriptor: | (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, Neuropilin-1 | Authors: | Yelland, T, Djordjevic, S, Fotinou, K, Selwood, D, Zachary, I, Frankel, P. | Deposit date: | 2018-01-30 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (0.9 Å) | Cite: | Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells. J. Med. Chem., 61, 2018
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2KD7
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![BU of 2kd7 by Molmil](/molmil-images/mine/2kd7) | Solution NMR structure of F5/8 type C-terminal domain of a putative chitobiase from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium target BtR324B | Descriptor: | Putative chitobiase | Authors: | Eletsky, A, Mills, J.L, Lee, H, Lee, D, Jiang, M, Ciccosanti, C, Xiao, R, Nair, R, Everett, J.K, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Prestegard, J.H, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-01-04 | Release date: | 2009-02-03 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of F5/8 type C-terminal domain of a putative chitobiase from Bacteroides thetaiotaomicron. To be Published
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2Z4F
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![BU of 2z4f by Molmil](/molmil-images/mine/2z4f) | Solution structure of the Discoidin Domain of DDR2 | Descriptor: | Discoidin domain-containing receptor 2 | Authors: | Ichikawa, O, Osawa, M, Nishida, N, Goshima, N, Nomura, N, Shimada, I. | Deposit date: | 2007-06-16 | Release date: | 2007-09-04 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structural basis of the collagen-binding mode of discoidin domain receptor 2 Embo J., 26, 2007
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4RN5
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![BU of 4rn5 by Molmil](/molmil-images/mine/4rn5) | B1 domain of human Neuropilin-1 with acetate ion in a ligand-binding site | Descriptor: | ACETATE ION, GLYCEROL, Neuropilin-1, ... | Authors: | Allerston, C.K, Yelland, T.S, Jarvis, A, Jenkins, K, Winfield, N, Cheng, L, Jia, H, Zachary, I, Selwood, D.L, Djordjevic, S. | Deposit date: | 2014-10-23 | Release date: | 2015-10-28 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Conserved water molecules in a ligand-binding site of neuropilin-1 To be Published
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7RGA
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![BU of 7rga by Molmil](/molmil-images/mine/7rga) | Crystal structure of nanoCLAMP3:VHH in complex with MTX | Descriptor: | METHOTREXATE, SODIUM ION, nano CLostridial Antibody Mimetic Protein 3 VHH | Authors: | Guo, Z, Alexandrov, K. | Deposit date: | 2021-07-14 | Release date: | 2022-05-25 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Design of a methotrexate-controlled chemical dimerization system and its use in bio-electronic devices. Nat Commun, 12, 2021
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7S0P
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![BU of 7s0p by Molmil](/molmil-images/mine/7s0p) | Crystal structure of Porcine Factor VIII C2 Domain Bound to Phosphatidylserine | Descriptor: | Coagulation factor VIII, PHOSPHOSERINE | Authors: | Peters, S.C, Childers, K.C, Wo, S.W, Brison, C.M, Swanson, C.D, Spiegel, P.C. | Deposit date: | 2021-08-30 | Release date: | 2021-10-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Stable binding to phosphatidylserine-containing membranes requires conserved arginine residues in tandem C domains of blood coagulation factor VIII. Front Mol Biosci, 9, 2022
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4TXW
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![BU of 4txw by Molmil](/molmil-images/mine/4txw) | Crystal structure of CBM32-4 from the Clostridium perfringens NagH | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Hyaluronoglucosaminidase | Authors: | Grondin, J.M, Ficko-Blean, E, Boraston, A.B, Smith, S.P. | Deposit date: | 2014-07-07 | Release date: | 2015-12-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Solution Structure and Dynamics of Full-length GH84A, a multimodular B-N-acetylglucosaminidase from Clostridium perfringens To Be Published
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5N6W
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![BU of 5n6w by Molmil](/molmil-images/mine/5n6w) | Retinoschisin R141H Mutant | Descriptor: | Retinoschisin | Authors: | Ramsay, E.P, Collins, R.F, Owens, T.W, Siebert, C.A, Jones, R.P.O, Roseman, A, Wang, T, Baldock, C. | Deposit date: | 2017-02-16 | Release date: | 2017-04-12 | Last modified: | 2017-08-30 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural analysis of X-linked retinoschisis mutations reveals distinct classes which differentially effect retinoschisin function Human Molecular Genetics, 25, 2016
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5C7G
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7O1N
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1IQD
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![BU of 1iqd by Molmil](/molmil-images/mine/1iqd) | Human Factor VIII C2 Domain complexed to human monoclonal BO2C11 Fab. | Descriptor: | HUMAN FACTOR VIII, HUMAN MONOCLONAL BO2C11 FAB HEAVY CHAIN, HUMAN MONOCLONAL BO2C11 FAB LIGHT CHAIN | Authors: | Spiegel Jr, P.C, Jacquemin, M, Saint-Remy, J.M, Stoddard, B.L, Pratt, K.P. | Deposit date: | 2001-07-21 | Release date: | 2001-08-15 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of a factor VIII C2 domain-immunoglobulin G4kappa Fab complex: identification of an inhibitory antibody epitope on the surface of factor VIII. Blood, 98, 2001
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7P5U
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5DQ0
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![BU of 5dq0 by Molmil](/molmil-images/mine/5dq0) | Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | Authors: | Tsai, Y.I, Rana, R.R, Zachary, I, Djordjevic, S. | Deposit date: | 2015-09-14 | Release date: | 2016-09-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site To Be Published
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1TVG
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![BU of 1tvg by Molmil](/molmil-images/mine/1tvg) | X-ray structure of human PP25 gene product, HSPC034. Northeast Structural Genomics Target HR1958. | Descriptor: | CALCIUM ION, LOC51668 protein, SAMARIUM (III) ION | Authors: | Kuzin, A.P, Vorobiev, S.M, Lee, I, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-06-29 | Release date: | 2004-11-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Improving NMR protein structure quality by Rosetta refinement: a molecular replacement study. Proteins, 75, 2009
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