5J31
| Crystal structure of 14-3-3zeta in complex with an alkyne cross-linked cyclic peptide derived from ExoS | Descriptor: | 14-3-3 protein zeta/delta, BENZOIC ACID, Exoenzyme S | Authors: | Wallraven, K, Cromm, P, Bier, D, Glas, A, Grossmann, T. | Deposit date: | 2016-03-30 | Release date: | 2016-10-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Constraining an Irregular Peptide Secondary Structure through Ring-Closing Alkyne Metathesis. Chembiochem, 17, 2016
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5HZA
| Crystal structure of GII.10 P domain in complex with 3-fucosyllactose (3 FL) | Descriptor: | 1,2-ETHANEDIOL, Capsid protein, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]beta-D-glucopyranose | Authors: | Hansman, G.S, Koromyslova, A.D, Singh, B.K. | Deposit date: | 2016-02-02 | Release date: | 2016-03-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structural Basis for Norovirus Inhibition by Human Milk Oligosaccharides. J.Virol., 90, 2016
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196L
| THERMODYNAMIC AND STRUCTURAL COMPENSATION IN "SIZE-SWITCH" CORE-REPACKING VARIANTS OF T4 LYSOZYME | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME | Authors: | Baldwin, E, Xu, J, Hajiseyedjavadi, O, Matthews, B.W. | Deposit date: | 1995-11-06 | Release date: | 1996-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme. J.Mol.Biol., 259, 1996
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7RP4
| Crystal structure of KRAS G12C in complex with GNE-1952 | Descriptor: | 1-[4-[6-chloranyl-7-(5-methyl-1~{H}-indazol-4-yl)quinazolin-4-yl]piperazin-1-yl]propan-1-one, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Oh, A, Tam, C, Wang, W. | Deposit date: | 2021-08-03 | Release date: | 2022-03-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors. Nat.Biotechnol., 40, 2022
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5JM0
| Structure of the S. cerevisiae alpha-mannosidase 1 | Descriptor: | Alpha-mannosidase,Alpha-mannosidase,Alpha-mannosidase | Authors: | Schneider, S, Kosinski, J, Jakobi, A.J, Hagen, W.J.H, Sachse, C. | Deposit date: | 2016-04-28 | Release date: | 2016-06-15 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | Higher-order assemblies of oligomeric cargo receptor complexes form the membrane scaffold of the Cvt vesicle. Embo Rep., 17, 2016
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1A3K
| X-RAY CRYSTAL STRUCTURE OF THE HUMAN GALECTIN-3 CARBOHYDRATE RECOGNITION DOMAIN (CRD) AT 2.1 ANGSTROM RESOLUTION | Descriptor: | GALECTIN-3, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Seetharaman, J, Kanigsberg, A, Slaaby, R, Leffler, H, Barondes, S.H, Rini, J.M. | Deposit date: | 1998-01-22 | Release date: | 1998-07-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | X-ray crystal structure of the human galectin-3 carbohydrate recognition domain at 2.1-A resolution. J.Biol.Chem., 273, 1998
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1KO5
| Crystal structure of gluconate kinase | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Gluconate kinase, MAGNESIUM ION | Authors: | Kraft, L, Sprenger, G.A, Lindqvist, Y. | Deposit date: | 2001-12-20 | Release date: | 2002-05-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Conformational changes during the catalytic cycle of gluconate kinase as revealed by X-ray crystallography. J.Mol.Biol., 318, 2002
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152L
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1A1Z
| FADD DEATH EFFECTOR DOMAIN, F25G MUTANT, NMR MINIMIZED AVERAGE STRUCTURE | Descriptor: | FADD PROTEIN | Authors: | Eberstadt, M, Huang, B, Chen, Z, Meadows, R.P, Ng, C, Fesik, S.W. | Deposit date: | 1997-12-18 | Release date: | 1998-12-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure and mutagenesis of the FADD (Mort1) death-effector domain. Nature, 392, 1998
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1KQJ
| Crystal Structure of a Mutant of MutY Catalytic Domain | Descriptor: | A/G-SPECIFIC ADENINE GLYCOSYLASE, GLYCEROL, IRON/SULFUR CLUSTER, ... | Authors: | Messick, T.E, Chmiel, N.H, Golinelli, M.P, David, S.S, Joshua-Tor, L. | Deposit date: | 2002-01-06 | Release date: | 2002-04-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Noncysteinyl coordination to the [4Fe-4S]2+ cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster. Biochemistry, 41, 2002
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178L
| Protein flexibility and adaptability seen in 25 crystal forms of T4 LYSOZYME | Descriptor: | CHLORIDE ION, T4 LYSOZYME | Authors: | Matsumura, M, Weaver, L, Zhang, X.-J, Matthews, B.W. | Deposit date: | 1995-03-24 | Release date: | 1995-07-10 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme. J.Mol.Biol., 250, 1995
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1AGF
| ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKRYKL-5R MUTATION) | Descriptor: | B*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGKKRYKL - 5R MUTATION) | Authors: | Reid, S.W, Mcadam, S, Smith, K.J, Klenerman, P, O'Callaghan, C.A, Harlos, K, Jakobsen, B.K, Mcmichael, A.J, Bell, J, Stuart, D.I, Jones, E.Y. | Deposit date: | 1997-03-24 | Release date: | 1997-06-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Antagonist HIV-1 Gag peptides induce structural changes in HLA B8. J.Exp.Med., 184, 1996
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1OKX
| Binding Structure of Elastase Inhibitor Scyptolin A | Descriptor: | ELASTASE 1, SCYPTOLIN A | Authors: | Matern, U, Schleberger, C, Jelakovic, S, Weckesser, J, Schulz, G.E. | Deposit date: | 2003-07-31 | Release date: | 2003-10-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Binding Structure of Elastase Inhibitor Scyptolin A Chem.Biol., 10, 2003
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198L
| THERMODYNAMIC AND STRUCTURAL COMPENSATION IN "SIZE-SWITCH" CORE-REPACKING VARIANTS OF T4 LYSOZYME | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME | Authors: | Baldwin, E, Xu, J, Hajiseyedjavadi, O, Matthews, B.W. | Deposit date: | 1995-11-06 | Release date: | 1996-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme. J.Mol.Biol., 259, 1996
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3E0D
| Insights into the Replisome from the Crystral Structure of the Ternary Complex of the Eubacterial DNA Polymerase III alpha-subunit | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase III subunit alpha, ... | Authors: | Wing, R.A, Bailey, S, Steitz, T.A. | Deposit date: | 2008-07-31 | Release date: | 2008-09-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4.6 Å) | Cite: | Insights into the Replisome from the Structure of a Ternary Complex of the DNA Polymerase III alpha-Subunit. J.Mol.Biol., 382, 2008
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1KV4
| Solution structure of antibacterial peptide (Moricin) | Descriptor: | moricin | Authors: | Hemmi, H, Ishibashi, J, Hara, S, Yamakawa, M. | Deposit date: | 2002-01-25 | Release date: | 2002-05-22 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of moricin, an antibacterial peptide, isolated from the silkworm Bombyx mori. FEBS Lett., 518, 2002
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1AKJ
| COMPLEX OF THE HUMAN MHC CLASS I GLYCOPROTEIN HLA-A2 AND THE T CELL CORECEPTOR CD8 | Descriptor: | BETA 2-MICROGLOBULIN, HIV REVERSE TRANSCRIPTASE EPITOPE, MHC CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A*0201) (ALPHA CHAIN), ... | Authors: | Tormo, J, Stuart, D.I, Jones, E.Y. | Deposit date: | 1997-05-21 | Release date: | 1997-09-17 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2. Nature, 387, 1997
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8P7G
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1KC8
| Co-crystal Structure of Blasticidin S Bound to the 50S Ribosomal Subunit | Descriptor: | 23S RRNA, 5S RRNA, BLASTICIDIN S, ... | Authors: | Hansen, J.L, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A. | Deposit date: | 2001-11-07 | Release date: | 2003-07-22 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of
the Large Ribosomal Subunit J.Mol.Biol., 330, 2003
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165L
| CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME | Authors: | Blaber, M, Matthews, B.W. | Deposit date: | 1994-06-20 | Release date: | 1994-08-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent. J.Mol.Biol., 246, 1995
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172L
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7CQ1
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7CFV
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3DL9
| Crystal structure of CYP2R1 in complex with 1-alpha-hydroxy-vitamin D2 | Descriptor: | (1S,3R,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraene-1,3-diol, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), Cytochrome P450 2R1, ... | Authors: | Strushkevich, N.V, Tempel, W, Gilep, A.A, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Wilkstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-06-26 | Release date: | 2008-08-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.721 Å) | Cite: | Crystal structure of CYP2R1 in complex with 1-alpha-hydroxy-vitamin D2. To be Published
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1JKT
| TETRAGONAL CRYSTAL FORM OF A CATALYTIC DOMAIN OF DEATH-ASSOCIATED PROTEIN KINASE | Descriptor: | DEATH-ASSOCIATED PROTEIN KINASE | Authors: | Tereshko, V, Teplova, M, Brunzelle, J, Watterson, D.M, Egli, M. | Deposit date: | 2001-07-13 | Release date: | 2002-04-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Crystal structures of the catalytic domain of human protein kinase associated with apoptosis and tumor suppression. Nat.Struct.Biol., 8, 2001
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