Co-crystal Structure of Blasticidin S Bound to the 50S Ribosomal Subunit

Summary for 1KC8

Related1K73 1K8A 1K9M 1KD1
Descriptor23S RRNA, 5S RRNA, RIBOSOMAL PROTEIN L2, ... (37 entities in total)
Functional Keywords50s subunit, blasticidin s, antibiotic, p-loop, p-site, ribosome
Biological sourceHaloarcula marismortui
Total number of polymer chains30
Total molecular weight1459039.17
Hansen, J.L.,Ban, N.,Nissen, P.,Moore, P.B.,Steitz, T.A. (deposition date: 2001-11-07, release date: 2003-07-22, Last modification date: 2011-07-13)
Primary citation
Hansen, J.,Moore, P.B.,Steitz, T.A.
Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit
J.Mol.Biol., 330:1061-1075, 2003
PubMed: 12860128 (PDB entries with the same primary citation)
DOI: 10.1016/S0022-2836(03)00668-5
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone201.6%5.3%5.2%0.65MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1kc8
no rotation
Molmil generated image of 1kc8
rotated about x axis by 90°
Molmil generated image of 1kc8
rotated about y axis by 90°