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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

1KC8

Co-crystal Structure of Blasticidin S Bound to the 50S Ribosomal Subunit

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)		23S RRNApolymer2922946034.41GenBank (3377779)Haloarcula marismortui
2B
(B)		5S RRNApolymer12239318.41GenBank (3377779)Haloarcula marismortui
3C
(C)		RIBOSOMAL PROTEIN L2polymer23925237.51UniProt (P20276)
Pfam (PF00181)
Pfam (PF03947)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L2P, HMAL2, HL4
4D
(D)		RIBOSOMAL PROTEIN L3polymer33737265.21UniProt (P20279)
Pfam (PF00297)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L3P, HMAL3, HL1
5E
(E)		RIBOSOMAL PROTEIN L4polymer24626442.11UniProt (P12735)
Pfam (PF00573)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L4E, HMAL4, HL6
6F
(F)		RIBOSOMAL PROTEIN L5polymer17619420.51UniProt (P14124)
Pfam (PF00673)
Pfam (PF00281)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L5P, HMAL5, HL13
7G
(G)		RIBOSOMAL PROTEIN L6polymer17719830.51UniProt (P14135)
Pfam (PF00347)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L6P, HMAL6, HL10
8H
(H)		RIBOSOMAL PROTEIN L7AEpolymer11912600.81UniProt (P12743)
Pfam (PF01248)		Haloarcula marismortui50S RIBOSOMAL PROTEIN HS6
9I
(I)		RIBOSOMAL PROTEIN L10polymer34837213.81UniProt (P15825)
Pfam (PF00466)
Pfam (PF17777)		Haloarcula marismortui50S RIBOSOMAL PROTEIN P0, HMAL10, L10E
10J
(J)		RIBOSOMAL PROTEIN L10Epolymer16718022.51Pfam (PF00252)
UniProt (by SIFTS) (P60617)		Haloarcula marismortui
11K
(K)		RIBOSOMAL PROTEIN L13polymer14516249.21UniProt (P29198)
Pfam (PF00572)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L13P, HMAL13
12L
(L)		RIBOSOMAL PROTEIN L14polymer13214216.21UniProt (P22450)
Pfam (PF00238)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L14P, HMAL14, HL27
13M
(M)		RIBOSOMAL PROTEIN L15polymer16417874.21UniProt (P12737)
Pfam (PF00828)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L15P, HMAL15, HL9
14N
(N)		RIBOSOMAL PROTEIN L15Epolymer19422856.61Pfam (PF00827)
UniProt (by SIFTS) (P60618)		Haloarcula marismortui
15O
(O)		RIBOSOMAL PROTEIN L18polymer18620509.71UniProt (P14123)
Pfam (PF17144)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L18P, HMAL18, HL12
16P
(P)		RIBOSOMAL PROTEIN L18Epolymer11512307.71UniProt (P12733)
Pfam (PF00828)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L18E, HL29, L19
17Q
(Q)		RIBOSOMAL PROTEIN L19Epolymer14816631.31UniProt (P14119)
Pfam (PF01280)
Pfam (PF25476)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L19E, HMAL19, HL24
18R
(R)		RIBOSOMAL PROTEIN L21Epolymer9510436.61UniProt (P12734)
Pfam (PF01157)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L21E, HL31
19S
(S)		RIBOSOMAL PROTEIN L22polymer15416835.71UniProt (P10970)
Pfam (PF00237)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L22P, HMAL22, HL23
20T
(T)		RIBOSOMAL PROTEIN L23polymer849481.31UniProt (P12732)
Pfam (PF00276)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L23P, HMAL23, HL25, L21
21U
(U)		RIBOSOMAL PROTEIN L24polymer11913539.81UniProt (P10972)
Pfam (PF16906)
Pfam (PF00467)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L24P, HMAL24, HL16, HL15
22V
(V)		RIBOSOMAL PROTEIN L24Epolymer667233.71UniProt (P14116)
Pfam (PF01246)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L24E, HL21/HL22
23W
(W)		RIBOSOMAL PROTEIN L29polymer707758.71UniProt (P10971)
Pfam (PF00831)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L29P, HMAL29, HL33
24X
(X)		RIBOSOMAL PROTEIN L30polymer15417062.91UniProt (P14121)
Pfam (PF00327)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L30P, HMAL30, HL20, HL16
25Y
(Y)		RIBOSOMAL PROTEIN L31Epolymer9110253.41UniProt (P18138)
Pfam (PF01198)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L31E, L34, HL30
26Z
(Z)		RIBOSOMAL PROTEIN L32Epolymer24026324.51UniProt (P12736)
Pfam (PF14520)
Pfam (PF01655)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L32E, HL5
27AA
(1)		RIBOSOMAL PROTEIN L37Aepolymer738097.81Pfam (PF01780)
UniProt (by SIFTS) (P60619)		Haloarcula marismortui
28BA
(2)		RIBOSOMAL PROTEIN L37Epolymer566199.01UniProt (P32410)
Pfam (PF01907)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L37E, L35E
29CA
(3)		RIBOSOMAL PROTEIN L39Epolymer485844.71UniProt (P22452)
Pfam (PF00832)		Haloarcula marismortui50S RIBOSOMAL PROTEINS L39E, HL39E, HL46E
30DA
(4)		RIBOSOMAL PROTEIN L44Epolymer9210815.21UniProt (P32411)
Pfam (PF00935)		Haloarcula marismortui50S RIBOSOMAL PROTEIN L44E, LA, HLA
31EA, FA
(A)		BLASTICIDIN Snon-polymer422.42Chemie (BLS)
PubChem (16667710)
PubChem (16758236)
PubChem (16760316)
PubChem (16760318)
PubChem (18772420)
PubChem (21124837)
PubChem (258)
PubChem (23818608)
PubChem (25078184)
PubChem (16380)
PubChem (44119963)
PubChem (170012)
PubChem (439625)
PubChem (5352011)
PubChem (5745696)
PubChem (124080961)
PubChem (124351418)
PubChem (12300172)
PubChem (124918591)
PubChem (132285147)
PubChem (138107250)
PubChem (162939623)
PubChem (16211310)
32AB, AC, AD, AE, BB...
(A, 4, L, B, C...)		MAGNESIUM IONnon-polymer24.3117Chemie (MG)
PubChem (888)
33ME, NE, OE
(A)		POTASSIUM IONnon-polymer39.13Chemie (K)
PubChem (813)
34AF, AG, AH, AI, BF...
(A, J, K, M, N...)		SODIUM IONnon-polymer23.086Chemie (NA)
PubChem (923)
35CI, DI, EI, EJ, FI...
(K, 4, A, M, N...)		CHLORIDE IONnon-polymer35.522Chemie (CL)
PubChem (312)
36AJ, BJ, DJ, MI, WI
(1, 2, 4, P, V)		CADMIUM IONnon-polymer112.45Chemie (CD)
PubChem (31193)
37AK, BK, CK, DK, EK...
(V, W, X, Y, Z...)		waterwater18.07879Chemie (HOH)
Sequence modifications
A: 2 - 2923 (GenBank: 3377779)
PDBExternal DatabaseDetails
C 560U 3155conflict
D: 1 - 337 (UniProt: P20279)
PDBExternal DatabaseDetails
-Pro 310deletion
Arg 310Phe 311conflict
Q: 1 - 148 (UniProt: P14119)
PDBExternal DatabaseDetails
Lys 71Tyr 71conflict
3: 1 - 48 (UniProt: P22452)
PDBExternal DatabaseDetails
-Arg 31deletion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains30
Total formula weight1451914.1
Non-Polymers*Number of molecules235
Total formula weight7125.0
All*Total formula weight1459039.2
*Water molecules are not included.

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PDB entries from 2026-05-06

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