8FKP
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![BU of 8fkp by Molmil](/molmil-images/mine/8fkp) | |
5GAG
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![BU of 5gag by Molmil](/molmil-images/mine/5gag) | RNC in complex with SRP-SR in the closed state | Descriptor: | 1A9L SS, 23S rRNA, 50S ribosomal protein L10, ... | Authors: | Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N. | Deposit date: | 2015-11-26 | Release date: | 2016-01-27 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon. Nat Commun, 7, 2016
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5GAF
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![BU of 5gaf by Molmil](/molmil-images/mine/5gaf) | RNC in complex with SRP | Descriptor: | 1A9L SS, 23S ribosomal RNA, 50S ribosomal protein L10, ... | Authors: | Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N. | Deposit date: | 2015-11-25 | Release date: | 2016-02-03 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon Nat Commun, 7, 2016
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5GAH
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![BU of 5gah by Molmil](/molmil-images/mine/5gah) | RNC in complex with SRP with detached NG domain | Descriptor: | 1A9L SS, 23S rRNA, 50S ribosomal protein L10, ... | Authors: | Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N. | Deposit date: | 2015-11-26 | Release date: | 2016-01-27 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon. Nat Commun, 7, 2016
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5GAE
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![BU of 5gae by Molmil](/molmil-images/mine/5gae) | RNC in complex with a translocating SecYEG | Descriptor: | 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | Authors: | Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N. | Deposit date: | 2015-11-25 | Release date: | 2016-01-27 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon. Nat Commun, 7, 2016
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7EGI
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![BU of 7egi by Molmil](/molmil-images/mine/7egi) | TFIID in rearranged conformation | Descriptor: | TATA-box-binding protein, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (9.82 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGE
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![BU of 7ege by Molmil](/molmil-images/mine/7ege) | TFIID in canonical conformation | Descriptor: | TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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6H1C
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![BU of 6h1c by Molmil](/molmil-images/mine/6h1c) | Structure of Ferric uptake regulator from Pseudomonas aeruginosa with manganese. | Descriptor: | Ferric uptake regulation protein, MANGANESE (II) ION, ZINC ION | Authors: | Nader, S, Perard, J, Carpentier, P, Michaud-Soret, I, Crouzy, S. | Deposit date: | 2018-07-11 | Release date: | 2019-07-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Ferric uptake regulator with Mn and Zn form Pseudomonas aeruginosa To Be Published
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8FKR
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![BU of 8fkr by Molmil](/molmil-images/mine/8fkr) | |
8E42
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![BU of 8e42 by Molmil](/molmil-images/mine/8e42) | E. coli 50S ribosome bound to tiamulin and azithromycin | Descriptor: | 50S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L15, ... | Authors: | Pellegrino, J, Lee, D.J, Fraser, J.S, Seiple, I.B. | Deposit date: | 2022-08-17 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (2.29 Å) | Cite: | Tiamulin and NPET binders To Be Published
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8E35
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![BU of 8e35 by Molmil](/molmil-images/mine/8e35) | E. coli 50S ribosome bound to compound SAB002 | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L15, ... | Authors: | Pellegrino, J, Lee, D.J, Fraser, J.S, Seiple, I.B. | Deposit date: | 2022-08-16 | Release date: | 2023-06-28 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.27 Å) | Cite: | Potential for clicked streptogramin analogs To Be Published
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8E47
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![BU of 8e47 by Molmil](/molmil-images/mine/8e47) | E. coli 50S ribosome bound to antibiotic analog SLC26 | Descriptor: | (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-({3,4,6-trideoxy-3-[(2-{[2-({[(5S)-3-{(4M)-3-fluoro-4-[(6P)-6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl}amino)-2-oxoethyl]sulfanyl}ethyl)(methyl)amino]-beta-D-xylo-hexopyranosyl}oxy)-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside, 23S ribosomal RNA, 50S ribosomal protein L13, ... | Authors: | Pellegrino, J, Lee, D.J, Fraser, J.S, Seiple, I.B. | Deposit date: | 2022-08-17 | Release date: | 2023-06-28 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.32 Å) | Cite: | SLC collection of antibiotic analogs To Be Published
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8E3O
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![BU of 8e3o by Molmil](/molmil-images/mine/8e3o) | E. coli 50S ribosome bound to solithromycin and VM1 | Descriptor: | (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 23S ribosomal RNA, 50S ribosomal protein L13, ... | Authors: | Pellegrino, J, Lee, D.J, Fraser, J.S, Seiple, I.B. | Deposit date: | 2022-08-17 | Release date: | 2023-06-28 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (1.99 Å) | Cite: | Solithromycin siderophore conjugates To Be Published
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8E3L
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![BU of 8e3l by Molmil](/molmil-images/mine/8e3l) | E. coli 50S ribosome bound to D-linker solithromycin conjugate | Descriptor: | (2~{R})-~{N}-[(2~{R})-6-azanyl-1-[[(2~{R})-1-[[(2~{R})-1-[[3-[1-[4-[(1~{S},2~{R},5~{S},7~{R},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-5-fluoranyl-9-methoxy-1,5,7,11,13-pentamethyl-4,6,12,16-tetrakis(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-15-yl]butyl]-1,2,3-triazol-4-yl]phenyl]amino]-4-methylsulfanyl-1-oxidanylidene-butan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-hexan-2-yl]-1-[(2~{R})-2-[[(2~{R})-2-[2-[[2,3-bis(oxidanyl)phenyl]carbonyl-[4-[[2,3-bis(oxidanyl)phenyl]carbonylamino]butyl]amino]ethanoylamino]-3-(1~{H}-indol-3-yl)propanoyl]amino]-3-oxidanyl-propanoyl]pyrrolidine-2-carboxamide, 50S ribosomal RNA, 50S ribosomal protein L13, ... | Authors: | Pellegrino, J, Lee, D.J, Fraser, J.S, Seiple, I.B. | Deposit date: | 2022-08-17 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (2.35 Å) | Cite: | Solithromycin siderophore conjugates To Be Published
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8E49
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![BU of 8e49 by Molmil](/molmil-images/mine/8e49) | E. coli 50S ribosome bound to antibiotic analog SLC31 | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L15, ... | Authors: | Pellegrino, J, Lee, D.J, Fraser, J.S, Seiple, I.B. | Deposit date: | 2022-08-17 | Release date: | 2023-06-28 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.05 Å) | Cite: | SLC collection of antibiotic analogs To Be Published
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8E43
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![BU of 8e43 by Molmil](/molmil-images/mine/8e43) | E. coli 50S ribosome bound to compound streptogramin A analog 3336 | Descriptor: | (2R)-2-[(3S,4R,5E,10E,12E,14S,16R,23S,26aR)-16-fluoro-14-hydroxy-12-methyl-1,7,22-trioxo-4-(prop-2-en-1-yl)-4,7,8,9,14,15,16,17,24,25,26,26a-dodecahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosin-3-yl]propyl isoquinolin-3-ylcarbamate, 23S ribosomal RNA, 50S ribosomal protein L13, ... | Authors: | Pellegrino, J, Lee, D.J, Seiple, I.B, Fraser, J.S. | Deposit date: | 2022-08-17 | Release date: | 2023-06-28 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.09 Å) | Cite: | Streptogramin A analogs To Be Published
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8E33
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![BU of 8e33 by Molmil](/molmil-images/mine/8e33) | E. coli 50S ribosome bound to compound streptogramin analog SAB001 | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L15, ... | Authors: | Pellegrino, J, Lee, D.J, Fraser, J.S, Seiple, I.B. | Deposit date: | 2022-08-16 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (2.23 Å) | Cite: | Potential for clicked streptogramin analogs To Be Published
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8E48
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![BU of 8e48 by Molmil](/molmil-images/mine/8e48) | E. coli 50S ribosome bound to antibiotic analog SLC30 | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L15, ... | Authors: | Pellegrino, J, Lee, D.J, Fraser, J.S, Seiple, I.B. | Deposit date: | 2022-08-17 | Release date: | 2023-06-28 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.27 Å) | Cite: | SLC collection of antibiotic analogs To Be Published
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8E46
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![BU of 8e46 by Molmil](/molmil-images/mine/8e46) | E. coli 50S ribosome bound to antibiotic analog SLC21 | Descriptor: | (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-({3,4,6-trideoxy-3-[{[1-(2-{[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]amino}-2-oxoethyl)-1H-1,2,3-triazol-4-yl]methyl}(methyl)amino]-beta-D-xylo-hexopyranosyl}oxy)-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside, 23S ribosomal RNA, 50S ribosomal protein L13, ... | Authors: | Pellegrino, J, Lee, D.J, Fraser, J.S, Seiple, I.B. | Deposit date: | 2022-08-17 | Release date: | 2023-06-28 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.32 Å) | Cite: | SLC collection of antibiotic analogs To Be Published
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8FKS
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![BU of 8fks by Molmil](/molmil-images/mine/8fks) | |
5UXX
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![BU of 5uxx by Molmil](/molmil-images/mine/5uxx) | |
7EDS
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![BU of 7eds by Molmil](/molmil-images/mine/7eds) | |
7EEU
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![BU of 7eeu by Molmil](/molmil-images/mine/7eeu) | |
8E30
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![BU of 8e30 by Molmil](/molmil-images/mine/8e30) | E. coli 50S ribosome bound to compound streptogramin A analog 3142 | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L15, ... | Authors: | Pellegrino, J, Lee, D.J, Fraser, J.S, Seiple, I.B. | Deposit date: | 2022-08-16 | Release date: | 2023-06-28 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (1.91 Å) | Cite: | Potential for clicked streptogramin analogs To Be Published
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8E36
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![BU of 8e36 by Molmil](/molmil-images/mine/8e36) | E. coli 50S ribosome bound to compound streptogramin A analog 3146 | Descriptor: | 2-[(3R,4R,5E,10E,12E,14S,16R,23S,26aR)-16-fluoro-14-hydroxy-12-methyl-1,7,22-trioxo-3-(propan-2-yl)-4,7,8,9,14,15,16,17,24,25,26,26a-dodecahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosin-4-yl]-N-{2-[4-(pyridin-4-yl)-1H-1,2,3-triazol-1-yl]ethyl}acetamide, 23S ribosomal RNA, 50S ribosomal protein L13, ... | Authors: | Pellegrino, J, Lee, D.J, Fraser, J.S, Seiple, I.B. | Deposit date: | 2022-08-16 | Release date: | 2023-06-28 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.38 Å) | Cite: | Potential for clicked streptogramin analogs To Be Published
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