8E3O

E. coli 50S ribosome bound to solithromycin and VM1

This is a non-PDB format compatible entry.

Summary for 8E3O

• Entry DOI: 10.2210/pdb8e3o/pdb
• EMDB information: 27869
• Descriptor: 23S ribosomal RNA, 50S ribosomal protein L34, (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, ... (12 entities in total)
• Functional Keywords: e. coli ribosome, solithromycin, antibiotics, ribosome
• Biological source: Escherichia coli; More
• Total number of polymer chains: 10
• Total formula weight: 1110448.42

Authors

Pellegrino, J.,Lee, D.J.,Fraser, J.S.,Seiple, I.B. (deposition date: 2022-08-17, release date: 2023-06-28, Last modification date: 2024-06-12)

• Primary citation: Boyce, J.H.,Pellegrino, J.,Lee, D.J.,Ecker, A.K.,Seiple, I.B.,Fraser, J.S.; Solithromycin siderophore conjugates; To Be Published,

Experimental method

ELECTRON MICROSCOPY (1.99 Å)