8E46

E. coli 50S ribosome bound to antibiotic analog SLC21

This is a non-PDB format compatible entry.

Summary for 8E46

• Entry DOI: 10.2210/pdb8e46/pdb
• EMDB information: 27881
• Descriptor: 23S ribosomal RNA, 50S ribosomal protein L34, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-({3,4,6-trideoxy-3-[{[1-(2-{[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]amino}-2-oxoethyl)-1H-1,2,3-triazol-4-yl]methyl}(methyl)amino]-beta-D-xylo-hexopyranosyl}oxy)-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside, ... (11 entities in total)
• Functional Keywords: e. coli ribosome, antibiotics, ribosome
• Biological source: Escherichia coli; More
• Total number of polymer chains: 10
• Total formula weight: 1110146.07

Authors

Pellegrino, J.,Lee, D.J.,Fraser, J.S.,Seiple, I.B. (deposition date: 2022-08-17, release date: 2023-06-28)

• Primary citation: Yeon, S.K.,Pellegrino, J.,Lee, D.J.,Seiple, I.B.,Fraser, J.S.; SLC collection of antibiotic analogs; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.32 Å)