8E36

E. coli 50S ribosome bound to compound streptogramin A analog 3146

This is a non-PDB format compatible entry.

Summary for 8E36

• Entry DOI: 10.2210/pdb8e36/pdb
• EMDB information: 27852 27854 27855 27857 27858
• Descriptor: 23S ribosomal RNA, 50S ribosomal protein L34, 2-[(3R,4R,5E,10E,12E,14S,16R,23S,26aR)-16-fluoro-14-hydroxy-12-methyl-1,7,22-trioxo-3-(propan-2-yl)-4,7,8,9,14,15,16,17,24,25,26,26a-dodecahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosin-4-yl]-N-{2-[4-(pyridin-4-yl)-1H-1,2,3-triazol-1-yl]ethyl}acetamide, ... (11 entities in total)
• Functional Keywords: e. coli ribosome, streptogramin a, antibiotics, ribosome-antibiotic complex, ribosome/antibiotic
• Biological source: Escherichia coli; More
• Total number of polymer chains: 10
• Total formula weight: 1109824.64

Authors

Pellegrino, J.,Lee, D.J.,Fraser, J.S.,Seiple, I.B. (deposition date: 2022-08-16, release date: 2023-06-28)

• Primary citation: Li, Q.,Pellegrino, J.,Lee, D.J.,Seiple, I.B.,Fraser, J.S.; Potential for clicked streptogramin analogs; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.38 Å)