8E48

E. coli 50S ribosome bound to antibiotic analog SLC30

This is a non-PDB format compatible entry.

Summary for 8E48

• Entry DOI: 10.2210/pdb8e48/pdb
• EMDB information: 27883
• Descriptor: 23S ribosomal RNA, 50S ribosomal protein L34, [(2~{S},3~{S},4~{R},6~{R})-4-[[2-[[(5~{S})-3-[3-fluoranyl-4-[6-(2-methyl-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl]-2-oxidanylidene-1,3-oxazolidin-5-yl]methylamino]-2-oxidanylidene-ethyl]-methyl-amino]-6-methyl-2-(phenylcarbonyloxy)oxan-3-yl] benzoate, ... (11 entities in total)
• Functional Keywords: antibiotics, ribosome
• Biological source: Escherichia coli; More
• Total number of polymer chains: 10
• Total formula weight: 1109856.60

Authors

Pellegrino, J.,Lee, D.J.,Fraser, J.S.,Seiple, I.B. (deposition date: 2022-08-17, release date: 2023-06-28, Last modification date: 2025-03-19)

• Primary citation: Yeon, S.K.,Pellegrino, J.,Lee, D.J.,Seiple, I.B.,Fraser, J.S.; SLC collection of antibiotic analogs; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.27 Å)