8E43

E. coli 50S ribosome bound to compound streptogramin A analog 3336

This is a non-PDB format compatible entry.

Summary for 8E43

• Entry DOI: 10.2210/pdb8e43/pdb
• EMDB information: 27878
• Descriptor: 23S ribosomal RNA, 50S ribosomal protein L34, (2R)-2-[(3S,4R,5E,10E,12E,14S,16R,23S,26aR)-16-fluoro-14-hydroxy-12-methyl-1,7,22-trioxo-4-(prop-2-en-1-yl)-4,7,8,9,14,15,16,17,24,25,26,26a-dodecahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosin-3-yl]propyl isoquinolin-3-ylcarbamate, ... (11 entities in total)
• Functional Keywords: ribosome, antibiotic, streptogramin a
• Biological source: Escherichia coli; More
• Total number of polymer chains: 10
• Total formula weight: 1109821.64

Authors

Pellegrino, J.,Lee, D.J.,Seiple, I.B.,Fraser, J.S. (deposition date: 2022-08-17, release date: 2023-06-28)

• Primary citation: Li, Q.,Pellegrino, J.,Lee, D.J.,Fraser, J.S.,Seiple, I.B.; Streptogramin A analogs; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.09 Å)