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7S7B
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Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1)
Descriptor: Exosome RNA helicase MTR4, RNA (46-MER), RNA-binding protein 7, ...
Authors:Puno, M.R, Lima, C.D.
Deposit date:2021-09-15
Release date:2022-06-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.
Cell, 185, 2022
7S7C
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BU of 7s7c by Molmil
Human Nuclear Exosome Targeting (NEXT) complex bound to RNA (substrate 2)
Descriptor: Exosome RNA helicase MTR4, RNA (30-MER), RNA-binding protein 7, ...
Authors:Puno, M.R, Lima, C.D.
Deposit date:2021-09-15
Release date:2022-06-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.
Cell, 185, 2022
7S3A
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BU of 7s3a by Molmil
Crystal structure of intact U2AF65 RRM-region bound to AdML-C5 oligonucleotide
Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*CP*U)-D(P*(BRU))-R(P*CP*C)-3'), SODIUM ION, Splicing factor U2AF 65 kDa subunit
Authors:Jenkins, J.L, Henderson, S, Kielkopf, C.L.
Deposit date:2021-09-05
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
7S3B
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Crystal structure of intact U2AF65 RRM-region bound to AdML-G5 oligonucleotide
Descriptor: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*GP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Jenkins, J.L, Henderson, S, Kielkopf, C.L.
Deposit date:2021-09-05
Release date:2022-05-25
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
7S3C
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Crystal structure of intact U2AF65 RRM-region bound to AdML-A5 oligonucleotide
Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*AP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Glasser, E, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2021-09-05
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
7QP7
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BU of 7qp7 by Molmil
Structure of the human 48S initiation complex in closed state (h48S AUG closed)
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N.
Deposit date:2022-01-03
Release date:2022-05-11
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Conformational rearrangements upon start codon recognition in human 48S translation initiation complex.
Nucleic Acids Res., 50, 2022
7QP6
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BU of 7qp6 by Molmil
Structure of the human 48S initiation complex in open state (h48S AUG open)
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N.
Deposit date:2022-01-03
Release date:2022-05-11
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Conformational rearrangements upon start codon recognition in human 48S translation initiation complex.
Nucleic Acids Res., 50, 2022
7Q4L
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BU of 7q4l by Molmil
The solution structure of hsDND1 RRM12 bound to CUUAUUUG RNA
Descriptor: Dead end protein homolog 1, RNA (5'-R(*CP*UP*UP*AP*UP*UP*UP*G)-3')
Authors:Duszczyk, M.M, Allain, F.H.T.
Deposit date:2021-10-31
Release date:2022-05-04
Last modified:2022-10-19
Method:SOLUTION NMR
Cite:The solution structure of Dead End bound to AU-rich RNA reveals an unusual mode of tandem RRM-RNA recognition required for mRNA regulation.
Nat Commun, 13, 2022
7ZEX
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BU of 7zex by Molmil
Complex Cyp33-RRMdelta alpha : UAAUGUCG RNA
Descriptor: Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, RNA (5'-R(*UP*AP*AP*UP*GP*UP*CP*G)-3')
Authors:Blatter, M, Allain, F, Meylan, C.
Deposit date:2022-03-31
Release date:2022-05-04
Last modified:2023-05-03
Method:SOLUTION NMR
Cite:RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.
Sci Adv, 9, 2023
7ZEY
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BU of 7zey by Molmil
Complex Cyp33-RRM : MLL1-PHD3
Descriptor: MLL cleavage product N320, Peptidyl-prolyl cis-trans isomerase E, ZINC ION
Authors:Blatter, M, Allain, F, Meylan, C.
Deposit date:2022-03-31
Release date:2022-04-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.
Sci Adv, 9, 2023
7ZEZ
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BU of 7zez by Molmil
Trimolecular complex Cyp33-RRMdelta alpha : MLL1-PHD3 : H3K4me3
Descriptor: Histone H3, Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, MLL cleavage product N320, ...
Authors:Blatter, M, Allain, F, Meylan, C.
Deposit date:2022-03-31
Release date:2022-04-13
Last modified:2023-05-03
Method:SOLUTION NMR
Cite:RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.
Sci Adv, 9, 2023
7ZEW
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BU of 7zew by Molmil
Complex Cyp33-RRM : AAUAAA RNA
Descriptor: Peptidyl-prolyl cis-trans isomerase E, RNA (5'-R(*AP*AP*UP*AP*AP*A)-3')
Authors:Blatter, M, Allain, F, Meylan, C.
Deposit date:2022-03-31
Release date:2022-04-13
Last modified:2023-05-03
Method:SOLUTION NMR
Cite:RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.
Sci Adv, 9, 2023
7ZEV
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BU of 7zev by Molmil
Free form of extended Cyp33-RRM
Descriptor: Peptidyl-prolyl cis-trans isomerase E
Authors:Blatter, M, Allain, F, Meylan, C.
Deposit date:2022-03-31
Release date:2022-04-13
Last modified:2023-05-03
Method:SOLUTION NMR
Cite:RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.
Sci Adv, 9, 2023
7Q3L
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BU of 7q3l by Molmil
Human 17S U2 snRNP 5' domain
Descriptor: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ...
Authors:Tholen, J, Galej, W.P.
Deposit date:2021-10-28
Release date:2022-03-30
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structural basis of branch site recognition by the human spliceosome.
Science, 375, 2022
7Q4O
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BU of 7q4o by Molmil
Substrate-bound A-like U2 snRNP
Descriptor: BPS oligo, PHD finger-like domain-containing protein 5A, Splicing factor 3A subunit 2, ...
Authors:Tholen, J, Galej, W.P.
Deposit date:2021-11-01
Release date:2022-03-30
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Structural basis of branch site recognition by the human spliceosome.
Science, 375, 2022
7SLP
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BU of 7slp by Molmil
Cryo-EM structure of 7SK core RNP with linear RNA
Descriptor: 7SK snRNA methylphosphate capping enzyme, La-related protein 7, Linear 7SK RNA, ...
Authors:Yang, Y, Liu, S, Zhou, Z.H, Feigon, J.
Deposit date:2021-10-24
Release date:2022-03-30
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP.
Mol.Cell, 82, 2022
7SLQ
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BU of 7slq by Molmil
Cryo-EM structure of 7SK core RNP with circular RNA
Descriptor: 7SK snRNA methylphosphate capping enzyme, La-related protein 7, Minimal circular 7SK RNA, ...
Authors:Yang, Y, Liu, S, Zhou, Z.H, Feigon, J.
Deposit date:2021-10-24
Release date:2022-03-30
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP.
Mol.Cell, 82, 2022
7PU5
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BU of 7pu5 by Molmil
Structure of SFPQ-NONO complex
Descriptor: MAGNESIUM ION, Non-POU domain-containing octamer-binding protein, Splicing factor, ...
Authors:Fribourg, S.
Deposit date:2021-09-28
Release date:2022-03-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.999 Å)
Cite:Crystal structure of SFPQ-NONO heterodimer.
Biochimie, 198, 2022
7PY2
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BU of 7py2 by Molmil
Structure of pathological TDP-43 filaments from ALS with FTLD
Descriptor: TAR DNA-binding protein 43
Authors:Arseni, D, Hasegawa, H, Murzin, A.G, Kametani, F, Arai, M, Yoshida, M, Falcon, B.
Deposit date:2021-10-08
Release date:2021-12-15
Last modified:2022-01-19
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structure of pathological TDP-43 filaments from ALS with FTLD.
Nature, 601, 2022
7EB1
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BU of 7eb1 by Molmil
Solution NMR structure of the RRM domain of RNA binding protein RBM3 from homo sapiens
Descriptor: RNA-binding protein 3
Authors:Boral, S, Roy, S, Basak, A.J, Maiti, S, Lee, W, De, S.
Deposit date:2021-03-08
Release date:2021-12-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural and dynamic studies of the human RNA binding protein RBM3 reveals the molecular basis of its oligomerization and RNA recognition.
Febs J., 289, 2022
7OHR
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BU of 7ohr by Molmil
Nog1-TAP associated immature ribosomal particle population E from S. cerevisiae
Descriptor: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-10
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (4.72 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
7OHX
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BU of 7ohx by Molmil
Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL34 expression shut down, population A
Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-03
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
7OHS
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BU of 7ohs by Molmil
Nog1-TAP associated immature ribosomal particle population F from S. cerevisiae
Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-03
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (4.38 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
7OHW
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BU of 7ohw by Molmil
Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL25 expression shut down, population B
Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-03
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
7OHP
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BU of 7ohp by Molmil
Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL25 expression shut down, population A
Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-03
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021

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