7UJ1

Crystal structure of PSF-RNA complex

Summary for 7UJ1

Entry DOI	10.2210/pdb7uj1/pdb
Descriptor	Splicing factor, proline- and glutamine-rich, RNA (30-MER) (3 entities in total)
Functional Keywords	rna-recognition motif, dna binding, transcription regulation, polypyrimidine binding, rna binding protein-rna complex, rna binding protein/rna
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	113809.40
Authors	Sachpatzidis, A.,Wang, J.,Konigsberg, W.H. (deposition date: 2022-03-30, release date: 2022-09-28, Last modification date: 2023-10-18)
Primary citation	Wang, J.,Sachpatzidis, A.,Christian, T.D.,Lomakin, I.B.,Garen, A.,Konigsberg, W.H. Insight into the Tumor Suppression Mechanism from the Structure of Human Polypyrimidine Splicing Factor (PSF/SFPQ) Complexed with a 30mer RNA from Murine Virus-like 30S Transcript-1. Biochemistry, 61:1723-1734, 2022 Cited by PubMed: 35998361 DOI: 10.1021/acs.biochem.2c00192 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation