2PN6
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![BU of 2pn6 by Molmil](/molmil-images/mine/2pn6) | Crystal Structure of S32A of ST1022-Gln complex from Sulfolobus tokodaii | Descriptor: | 150aa long hypothetical transcriptional regulator, GLUTAMINE, MAGNESIUM ION | Authors: | Kumarevel, T.S, Karthe, P, Nakano, N, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-23 | Release date: | 2008-04-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding Nucleic Acids Res., 36, 2008
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2Q6S
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6XQD
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![BU of 6xqd by Molmil](/molmil-images/mine/6xqd) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UUC-mRNA, and deacylated P-site tRNA at 2.80A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Batool, Z, Lomakin, I.B, Bunick, C.G, Polikanov, Y.S. | Deposit date: | 2020-07-09 | Release date: | 2020-08-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Proc.Natl.Acad.Sci.USA, 117, 2020
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6XQE
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![BU of 6xqe by Molmil](/molmil-images/mine/6xqe) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UAA-mRNA, and deacylated P-site tRNA at 3.00A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Batool, Z, Lomakin, I.B, Bunick, C.G, Polikanov, Y.S. | Deposit date: | 2020-07-09 | Release date: | 2020-08-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Proc.Natl.Acad.Sci.USA, 117, 2020
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4W4Z
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![BU of 4w4z by Molmil](/molmil-images/mine/4w4z) | Structure of the EphA4 LBD in complex with peptide | Descriptor: | APY-bAla8.am peptide, Ephrin type-A receptor 4, GLYCEROL, ... | Authors: | Lechtenberg, B.C, Mace, P.D, Riedl, S.J. | Deposit date: | 2014-08-15 | Release date: | 2014-10-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Development and Structural Analysis of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor. Acs Chem.Biol., 9, 2014
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6DM0
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![BU of 6dm0 by Molmil](/molmil-images/mine/6dm0) | Open state GluA2 in complex with STZ and blocked by IEM-1460, after micelle signal subtraction | Descriptor: | CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, ... | Authors: | Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I. | Deposit date: | 2018-06-04 | Release date: | 2018-08-22 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors. Neuron, 99, 2018
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6DM1
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![BU of 6dm1 by Molmil](/molmil-images/mine/6dm1) | Open state GluA2 in complex with STZ and blocked by NASPM, after micelle signal subtraction | Descriptor: | CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, ... | Authors: | Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I. | Deposit date: | 2018-06-04 | Release date: | 2018-08-22 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors. Neuron, 99, 2018
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6DLZ
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![BU of 6dlz by Molmil](/molmil-images/mine/6dlz) | Open state GluA2 in complex with STZ after micelle signal subtraction | Descriptor: | CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit | Authors: | Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I. | Deposit date: | 2018-06-04 | Release date: | 2018-08-22 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors. Neuron, 99, 2018
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4NIE
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1AXY
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![BU of 1axy by Molmil](/molmil-images/mine/1axy) | ERYTHRINA CORALLODENDRON LECTIN | Descriptor: | CALCIUM ION, LECTIN, MANGANESE (II) ION, ... | Authors: | Shaanan, B, Elgavish, S. | Deposit date: | 1997-10-24 | Release date: | 1998-05-06 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structures of the Erythrina corallodendron lectin and of its complexes with mono- and disaccharides. J.Mol.Biol., 277, 1998
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1AX2
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4ROF
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![BU of 4rof by Molmil](/molmil-images/mine/4rof) | Crystal Structure of WW3 domain of ITCH in complex with TXNIP peptide | Descriptor: | E3 ubiquitin-protein ligase Itchy homolog, Thioredoxin-interacting protein | Authors: | Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2014-10-28 | Release date: | 2014-12-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Crystal Structure of WW3 domain of ITCH in complex with TXNIP peptide To be Published
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4UQQ
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![BU of 4uqq by Molmil](/molmil-images/mine/4uqq) | Electron density map of GluK2 desensitized state in complex with 2S,4R-4-methylglutamate | Descriptor: | GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2, GLUTAMIC ACID | Authors: | Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S. | Deposit date: | 2014-06-24 | Release date: | 2014-08-13 | Last modified: | 2017-08-02 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | Structural Mechanism of Glutamate Receptor Activation and Desensitization Nature, 514, 2014
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8CVK
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![BU of 8cvk by Molmil](/molmil-images/mine/8cvk) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMRC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.50A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. | Deposit date: | 2022-05-18 | Release date: | 2022-10-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes. Nat.Chem., 15, 2023
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8CVJ
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![BU of 8cvj by Molmil](/molmil-images/mine/8cvj) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMSEAC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.40A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. | Deposit date: | 2022-05-18 | Release date: | 2022-10-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes. Nat.Chem., 15, 2023
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8CVL
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![BU of 8cvl by Molmil](/molmil-images/mine/8cvl) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMTHSMRC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.30A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. | Deposit date: | 2022-05-18 | Release date: | 2022-10-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes. Nat.Chem., 15, 2023
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4N66
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![BU of 4n66 by Molmil](/molmil-images/mine/4n66) | Thermolysin in complex with UBTLN37 | Descriptor: | CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Krimmer, S.G, Heine, A, Klebe, G. | Deposit date: | 2013-10-11 | Release date: | 2014-04-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Methyl, Ethyl, Propyl, Butyl: Futile But Not for Water, as the Correlation of Structure and Thermodynamic Signature Shows in a Congeneric Series of Thermolysin Inhibitors. Chemmedchem, 4, 2014
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1TVK
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![BU of 1tvk by Molmil](/molmil-images/mine/1tvk) | The binding mode of epothilone A on a,b-tubulin by electron crystallography | Descriptor: | EPOTHILONE A, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Nettles, J.H, Li, H, Cornett, B, Krahn, J.M, Snyder, J.P, Downing, K.H. | Deposit date: | 2004-06-29 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | ELECTRON CRYSTALLOGRAPHY (2.89 Å) | Cite: | The binding mode of epothilone A on alpha,beta-tubulin by electron crystallography Science, 305, 2004
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6DR2
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![BU of 6dr2 by Molmil](/molmil-images/mine/6dr2) | Ca2+-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | CALCIUM ION, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-07-18 | Last modified: | 2018-08-15 | Method: | ELECTRON MICROSCOPY (4.33 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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6DQN
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![BU of 6dqn by Molmil](/molmil-images/mine/6dqn) | Class 1 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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6DQZ
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![BU of 6dqz by Molmil](/molmil-images/mine/6dqz) | Class 4 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (6.01 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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1UUD
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![BU of 1uud by Molmil](/molmil-images/mine/1uud) | NMR structure of a synthetic small molecule, rbt203, bound to HIV-1 TAR RNA | Descriptor: | N-[2-(2-{[(4-{[AMINO(IMINO)METHYL]AMINO}BUTYL)AMINO]METHYL}-4-METHOXYPHENOXY)ETHYL]GUANIDINE, RNA (5'-(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP *CP*CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C) -3') | Authors: | Davis, B, Afshar, M, Varani, G, Karn, J, Murchie, A.I.H, Lentzen, G, Drysdale, M.J, Potter, A.J, Bower, J, Aboul-Ela, F. | Deposit date: | 2003-12-18 | Release date: | 2004-03-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Rational Design of Inhibitors of HIV-1 Tar RNA Through the Stabilisation of Electrostatic "Hot Spots" J.Mol.Biol., 336, 2004
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6DA8
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![BU of 6da8 by Molmil](/molmil-images/mine/6da8) | Human CYP3A4 bound to an inhibitor | Descriptor: | Cytochrome P450 3A4, Nalpha-{(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl}-N-[(pyridin-3-yl)methyl]-D-phenylalaninamide, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sevrioukova, I.F. | Deposit date: | 2018-05-01 | Release date: | 2019-04-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.802 Å) | Cite: | Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
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6DQV
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![BU of 6dqv by Molmil](/molmil-images/mine/6dqv) | Class 2 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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3FTF
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![BU of 3ftf by Molmil](/molmil-images/mine/3ftf) | Crystal structure of A. aeolicus KsgA in complex with RNA and SAH | Descriptor: | 5'-R(P*AP*AP*CP*CP*GP*UP*AP*GP*GP*GP*GP*AP*AP*CP*CP*UP*GP*CP*GP*GP*UP*U)-3', Dimethyladenosine transferase, POTASSIUM ION, ... | Authors: | Tu, C, Ji, X. | Deposit date: | 2009-01-12 | Release date: | 2009-03-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis for Binding of RNA and Cofactor by a KsgA Methyltransferase. Structure, 17, 2009
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