8CVL
Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMTHSMRC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.30A resolution
This is a non-PDB format compatible entry.
Summary for 8CVL
| Entry DOI | 10.2210/pdb8cvl/pdb |
| Descriptor | 23S Ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (62 entities in total) |
| Functional Keywords | 70s ribosome, non-hydrolyzable, aminoacyl-trna, peptidyl-trna; formylation, pre-attack state, transpeptidation, peptidyl transferase center, nascent peptide exit tunnel, ribosome, ribosome-rna complex, ribosome/rna |
| Biological source | Escherichia coli More |
| Total number of polymer chains | 114 |
| Total formula weight | 4570642.99 |
| Authors | Syroegin, E.A.,Aleksandrova, E.V.,Polikanov, Y.S. (deposition date: 2022-05-18, release date: 2022-10-19, Last modification date: 2023-11-15) |
| Primary citation | Syroegin, E.A.,Aleksandrova, E.V.,Polikanov, Y.S. Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes. Nat.Chem., 15:143-153, 2023 Cited by PubMed: 36316410DOI: 10.1038/s41557-022-01073-1 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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