1TVK
The binding mode of epothilone A on a,b-tubulin by electron crystallography
Summary for 1TVK
Entry DOI | 10.2210/pdb1tvk/pdb |
Related | 1JFF 1TUB |
Descriptor | Tubulin alpha chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | epothilone; taxol; ligand interactions, cell cycle, structural protein |
Biological source | Bos taurus (cattle) More |
Total number of polymer chains | 2 |
Total formula weight | 98270.10 |
Authors | Nettles, J.H.,Li, H.,Cornett, B.,Krahn, J.M.,Snyder, J.P.,Downing, K.H. (deposition date: 2004-06-29, release date: 2004-09-14, Last modification date: 2023-08-23) |
Primary citation | Nettles, J.H.,Li, H.,Cornett, B.,Krahn, J.M.,Snyder, J.P.,Downing, K.H. The binding mode of epothilone A on alpha,beta-tubulin by electron crystallography Science, 305:866-869, 2004 Cited by PubMed: 15297674DOI: 10.1126/science.1099190 PDB entries with the same primary citation |
Experimental method | ELECTRON CRYSTALLOGRAPHY (2.89 Å) |
Structure validation
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