6DM0

Open state GluA2 in complex with STZ and blocked by IEM-1460, after micelle signal subtraction

Summary for 6DM0

• Entry DOI: 10.2210/pdb6dm0/pdb
• EMDB information: 7960
• Descriptor: Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, GLUTAMIC ACID, CYCLOTHIAZIDE, ... (4 entities in total)
• Functional Keywords: ion channel, transport protein
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 4
• Total formula weight: 463155.66

Authors

Twomey, E.C.,Yelshanskaya, M.V.,Vassilevski, A.A.,Sobolevsky, A.I. (deposition date: 2018-06-04, release date: 2018-08-22, Last modification date: 2019-12-18)

• Primary citation: Twomey, E.C.,Yelshanskaya, M.V.,Vassilevski, A.A.,Sobolevsky, A.I.; Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors.; Neuron, 99:956-968.e4, 2018; PubMed: 30122377; DOI: 10.1016/j.neuron.2018.07.027

Experimental method

ELECTRON MICROSCOPY (4.4 Å)