2Q6S
2.4 angstrom crystal structure of PPAR gamma complexed to BVT.13 without co-activator peptides
Summary for 2Q6S
Entry DOI | 10.2210/pdb2q6s/pdb |
Related | 2Q59 2Q5P 2Q5S 2Q61 2Q6R |
Descriptor | Peroxisome Proliferator-Activated Receptor gamma, 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID (3 entities in total) |
Functional Keywords | protein-ligand complex, ligand binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P37231 |
Total number of polymer chains | 2 |
Total formula weight | 62994.83 |
Authors | Bruning, J.B.,Nettles, K.W. (deposition date: 2007-06-01, release date: 2007-10-23, Last modification date: 2023-08-30) |
Primary citation | Bruning, J.B.,Chalmers, M.J.,Prasad, S.,Busby, S.A.,Kamenecka, T.M.,He, Y.,Nettles, K.W.,Griffin, P.R. Partial Agonists Activate PPARgamma Using a Helix 12 Independent Mechanism Structure, 15:1258-1271, 2007 Cited by PubMed: 17937915DOI: 10.1016/j.str.2007.07.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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