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3EGZ
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BU of 3egz by Molmil
Crystal structure of an in vitro evolved tetracycline aptamer and artificial riboswitch
Descriptor: 7-CHLOROTETRACYCLINE, MAGNESIUM ION, Tetracycline aptamer and artificial riboswitch, ...
Authors:Xiao, H, Edwards, T.E, Ferre-D'Amare, A.R.
Deposit date:2008-09-11
Release date:2008-10-28
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for specific, high-affinity tetracycline binding by an in vitro evolved aptamer and artificial riboswitch
Chem.Biol., 15, 2008
1O0P
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BU of 1o0p by Molmil
Solution Structure of the third RNA Recognition Motif (RRM) of U2AF65 in complex with an N-terminal SF1 peptide
Descriptor: Splicing Factor SF1, Splicing factor U2AF 65 kDa subunit
Authors:Selenko, P, Gregorovic, G, Sprangers, R, Stier, G, Rhani, Z, Kramer, A, Sattler, M.
Deposit date:2003-02-24
Release date:2003-05-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural Basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP
Mol.Cell, 11, 2003
3EGN
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BU of 3egn by Molmil
C-terminal RNA Recognition Motif of the U11/U12 65K Protein
Descriptor: RNA-binding protein 40
Authors:Netter, C, Wahl, M.C.
Deposit date:2008-09-11
Release date:2009-06-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Functional stabilization of an RNA recognition motif by a noncanonical N-terminal expansion
Rna, 15, 2009
6M75
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BU of 6m75 by Molmil
C-Myc DNA binding protein complex
Descriptor: DNA (5'-D(*TP*CP*TP*TP*AP*TP*T)-3'), RNA-binding motif, single-stranded-interacting protein 1, ...
Authors:Aggarwal, P, Bhavesh, N.S.
Deposit date:2020-03-17
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Hinge like domain motion facilitates human RBMS1 protein binding to proto-oncogene c-myc promoter.
Nucleic Acids Res., 49, 2021
4ED5
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BU of 4ed5 by Molmil
Crystal structure of the two N-terminal RRM domains of HuR complexed with RNA
Descriptor: 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, 5'-R(*A*UP*UP*UP*UP*UP*AP*UP*UP*UP*U)-3', ...
Authors:Wang, H, Zeng, F, Liu, Q, Niu, L, Teng, M, Li, X.
Deposit date:2012-03-27
Release date:2012-05-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA binding.
Acta Crystallogr.,Sect.D, 69, 2013
5O3J
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Crystal structure of TIA-1 RRM2 in complex with RNA
Descriptor: Nucleolysin TIA-1 isoform p40, RNA (5'-R(P*UP*UP*C)-3')
Authors:Sonntag, M, Jagtap, P.K.A, Hennig, J, Sattler, M.
Deposit date:2017-05-24
Release date:2017-07-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Segmental, Domain-Selective Perdeuteration and Small-Angle Neutron Scattering for Structural Analysis of Multi-Domain Proteins.
Angew. Chem. Int. Ed. Engl., 56, 2017
1PGZ
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Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Descriptor: 5'-D(*T*TP*AP*GP*GP*GP*TP*TP*AP*GP*(6MI)P*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Moore, S.A, Shamoo, Y.
Deposit date:2003-05-28
Release date:2003-11-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures
J.Biol.Chem., 278, 2003
6JVX
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Crystal structure of RBM38 in complex with RNA
Descriptor: RNA (5'-R(*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3'), RNA-binding protein 38, SULFATE ION
Authors:Qian, K, Li, M, Wang, J, Zhang, M, Wang, M.
Deposit date:2019-04-17
Release date:2020-01-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structural basis for mRNA recognition by human RBM38.
Biochem.J., 477, 2020
6N3D
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BU of 6n3d by Molmil
Structure of HIV Tat-specific factor 1 U2AF Homology Motif (APO-State)
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Loerch, S, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2018-11-15
Release date:2019-01-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface.
J. Biol. Chem., 294, 2019
1PO6
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BU of 1po6 by Molmil
Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
Descriptor: 5'-D(*T*AP*GP*GP*(6MI)P*TP*TP*AP*GP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Moore, S.A, Shamoo, Y.
Deposit date:2003-06-13
Release date:2003-11-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures
J.BIOL.CHEM., 278, 2003
1OIA
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U1A rnp domain 1-95
Descriptor: U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A
Authors:Nagai, K, Evans, P.R.
Deposit date:2003-06-12
Release date:2003-06-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the RNA-Binding Domain of the U1 Small Nuclear Ribonucleoprotein A
Nature, 348, 1990
6HIP
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BU of 6hip by Molmil
Structure of SPF45 UHM bound to HIV-1 Rev ULM
Descriptor: HIV-1 Rev (41-49), SODIUM ION, Splicing factor 45, ...
Authors:Pabis, M, Corsini, L, Sattler, M.
Deposit date:2018-08-30
Release date:2019-03-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors.
Nucleic Acids Res., 47, 2019
4CIO
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BU of 4cio by Molmil
RRM domain from C. elegans SUP-12 bound to GGUGUGC RNA
Descriptor: 5'-R(*GP*GP*UP*GP*UP*GP*CP)-3', PROTEIN SUP-12, ISOFORM A
Authors:Amrane, S, Mackereth, C.D.
Deposit date:2013-12-12
Release date:2014-09-03
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Backbone-Independent Nucleic Acid Binding by Splicing Factor Sup-12 Reveals Key Aspects of Molecular Recognition
Nat.Commun., 5, 2014
6NSX
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BU of 6nsx by Molmil
Yeast Hsh155 Ligand bound to Human Tat-SF1 Motif
Descriptor: CHLORIDE ION, HIV Tat-specific factor 1, Hsh155
Authors:Jenkins, J.L, Leach, J.R, Kielkopf, C.L.
Deposit date:2019-01-25
Release date:2019-06-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction.
Rna, 25, 2019
6NTY
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BU of 6nty by Molmil
2.1 A resolution structure of the Musashi-2 (Msi2) RNA recognition motif 1 (RRM1) domain
Descriptor: PHOSPHATE ION, RNA-binding protein Musashi homolog 2
Authors:Lovell, S, Kashipathy, M.M, Battaile, K.P, Lan, L, Xiaoqing, W, Cooper, A, Gao, F.P, Xu, L.
Deposit date:2019-01-30
Release date:2019-10-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal and solution structures of human oncoprotein Musashi-2 N-terminal RNA recognition motif 1.
Proteins, 88, 2020
6NWW
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BU of 6nww by Molmil
Crystal structure of the RRM domain of S. pombe Puf1 in the P212121 space group
Descriptor: CHLORIDE ION, Pumilio domain-containing protein C56F2.08c
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2019-02-07
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Distinct RNA-binding modules in a single PUF protein cooperate to determine RNA specificity.
Nucleic Acids Res., 47, 2019
1P1T
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BU of 1p1t by Molmil
NMR Structure of the N-terminal RRM domain of Cleavage stimulation factor 64 KDa subunit
Descriptor: Cleavage stimulation factor, 64 kDa subunit
Authors:Perez-Canadillas, J.M, Varani, G.
Deposit date:2003-04-14
Release date:2003-08-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein
Embo J., 22, 2003
1OPI
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BU of 1opi by Molmil
SOLUTION STRUCTURE OF THE THIRD RNA RECOGNITION MOTIF (RRM) OF U2AF65 IN COMPLEX WITH AN N-TERMINAL SF1 PEPTIDE
Descriptor: SPLICING FACTOR SF1, SPLICING FACTOR U2AF 65 KDA SUBUNIT
Authors:Selenko, P, Gregorovic, G, Sprangers, R, Stier, G, Rhani, Z, Kramer, A, Sattler, M.
Deposit date:2003-03-05
Release date:2004-03-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP
Mol.Cell, 11, 2003
6N3F
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BU of 6n3f by Molmil
Structure of HIV Tat-specific factor 1 U2AF Homology Motif bound to SF3b1 ULM5
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, HIV Tat-specific factor 1, ...
Authors:Leach, J.R, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2018-11-15
Release date:2019-01-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface.
J. Biol. Chem., 294, 2019
4F02
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BU of 4f02 by Molmil
Crystal structure of the PABP-binding site of eIF4G in complex with RRM1-2 of PABP and poly(A)
Descriptor: Eukaryotic translation initiation factor 4 gamma 1, Polyadenylate-binding protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
Authors:Safaee, N, Kozlov, G, Gehring, K.B.
Deposit date:2012-05-03
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
3G9C
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BU of 3g9c by Molmil
Crystal structure of the product Bacillus anthracis glmS ribozyme
Descriptor: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, GLMS RIBOZYME, MAGNESIUM ION, ...
Authors:Strobel, S.A, Cochrane, J.C, Lipchock, S.V, Smith, K.D.
Deposit date:2009-02-13
Release date:2009-11-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and chemical basis for glucosamine 6-phosphate binding and activation of the glmS ribozyme
Biochemistry, 48, 2009
6N3E
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BU of 6n3e by Molmil
Structure of HIV Tat-specific factor 1 U2AF Homology Motif bound to U2AF ligand motif 4
Descriptor: FORMIC ACID, GLYCEROL, HIV Tat-specific factor 1, ...
Authors:Loerch, S, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2018-11-15
Release date:2019-01-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.893 Å)
Cite:The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface.
J. Biol. Chem., 294, 2019
3G8T
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Crystal structure of the G33A mutant Bacillus anthracis glmS ribozyme bound to GlcN6P
Descriptor: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, RNA (5'-R(*AP*(A2M)P*GP*CP*GP*CP*CP*AP*GP*AP*AP*CP*U)-3'), ...
Authors:Strobel, S.A, Cochrane, J.C, Lipchock, S.V, Smith, K.D.
Deposit date:2009-02-12
Release date:2009-11-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and chemical basis for glucosamine 6-phosphate binding and activation of the glmS ribozyme
Biochemistry, 48, 2009
1NO8
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SOLUTION STRUCTURE OF THE NUCLEAR FACTOR ALY RBD DOMAIN
Descriptor: ALY
Authors:Perez-Alvarado, G.C, Martinez-Yamout, M, Allen, M.M, Grosschedl, R, Dyson, H.J, Wright, P.E.
Deposit date:2003-01-15
Release date:2003-08-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the Nuclear Factor ALY: Insights into Post-Transcriptional Regulatory and mRNA Nuclear Export Processes
Biochemistry, 42, 2003
1NU4
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U1A RNA binding domain at 1.8 angstrom resolution reveals a pre-organized C-terminal helix
Descriptor: MAGNESIUM ION, MALONIC ACID, U1A RNA binding domain
Authors:Rupert, P.B, Xiao, H, Ferre-D'Amare, A.R.
Deposit date:2003-01-30
Release date:2003-02-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:U1A RNA-binding domain at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003

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