4F02

Crystal structure of the PABP-binding site of eIF4G in complex with RRM1-2 of PABP and poly(A)

Summary for 4F02

• Entry DOI: 10.2210/pdb4f02/pdb
• Related: 4F25 4F26
• Descriptor: Polyadenylate-binding protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), Eukaryotic translation initiation factor 4 gamma 1, ... (4 entities in total)
• Functional Keywords: translation initiation, mrna, eukaryotic initiation factors (eifs), paip1 and paip2, translation-rna complex, translation/rna
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm : P11940
• Total number of polymer chains: 6
• Total formula weight: 60871.69

Authors

Safaee, N.,Kozlov, G.,Gehring, K.B. (deposition date: 2012-05-03, release date: 2012-08-08, Last modification date: 2024-02-28)

• Primary citation: Safaee, N.,Kozlov, G.,Noronha, A.M.,Xie, J.,Wilds, C.J.,Gehring, K.; Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.; Mol.Cell, 48:375-386, 2012; PubMed: 23041282; DOI: 10.1016/j.molcel.2012.09.001

Experimental method

X-RAY DIFFRACTION (2 Å)