4F02
Crystal structure of the PABP-binding site of eIF4G in complex with RRM1-2 of PABP and poly(A)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | Polyadenylate-binding protein 1 | polymer | 213 | 23833.1 | 2 | UniProt (P11940) Pfam (PF00076) In PDB | Homo sapiens (human) | PABP-1, Poly(A)-binding protein 1 |
2 | B, E | RNA (5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3') | polymer | 11 | 3576.3 | 2 | |||
3 | C, F | Eukaryotic translation initiation factor 4 gamma 1 | polymer | 27 | 3026.4 | 2 | UniProt (Q04637) In PDB | Homo sapiens | eIF-4-gamma 1, eIF-4G 1, eIF-4G1, p220 |
4 | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A, D: 1 - 190 (UniProt: P11940)
C, F: 178 - 203 (UniProt: Q04637)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Pro -3 | - | expression tag |
Leu -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Tyr 191 | - | expression tag |
Pro 192 | - | expression tag |
Tyr 193 | - | expression tag |
Asp 194 | - | expression tag |
Val 195 | - | expression tag |
Pro 196 | - | expression tag |
Asp 197 | - | expression tag |
Tyr 198 | - | expression tag |
Ala 199 | - | expression tag |
Gly 200 | - | expression tag |
Ser 201 | - | expression tag |
Ser 202 | - | expression tag |
Gly 203 | - | expression tag |
Arg 204 | - | expression tag |
Ile 205 | - | expression tag |
Val 206 | - | expression tag |
Thr 207 | - | expression tag |
Asp 208 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Tyr 204 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 60871.7 | |
All* | Total formula weight | 60871.7 |