3EGZ

Crystal structure of an in vitro evolved tetracycline aptamer and artificial riboswitch

Summary for 3EGZ

Entry DOI	10.2210/pdb3egz/pdb
Descriptor	U1 small nuclear ribonucleoprotein A, Tetracycline aptamer and artificial riboswitch, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	tetracycline, aptamer, riboswitch, antibiotic, rna
Biological source	Homo sapiens (Human) More
Cellular location	Nucleus: P09012
Total number of polymer chains	2
Total formula weight	33252.88
Authors	Xiao, H.,Edwards, T.E.,Ferre-D'Amare, A.R. (deposition date: 2008-09-11, release date: 2008-10-28, Last modification date: 2021-10-20)
Primary citation	Xiao, H.,Edwards, T.E.,Ferre-D'Amare, A.R. Structural basis for specific, high-affinity tetracycline binding by an in vitro evolved aptamer and artificial riboswitch Chem.Biol., 15:1125-1137, 2008 Cited by PubMed: 18940672 DOI: 10.1016/j.chembiol.2008.09.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation