3EGZ
Crystal structure of an in vitro evolved tetracycline aptamer and artificial riboswitch
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | U1 small nuclear ribonucleoprotein A | polymer | 98 | 11574.8 | 1 | UniProt (P09012) Pfam (PF00076) | Homo sapiens (Human) | U1 snRNP protein A, U1A protein, U1-A |
| 2 | B (B) | Tetracycline aptamer and artificial riboswitch | polymer | 65 | 20907.5 | 1 | |||
| 3 | C, E, F, G, H... (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) | |||
| 4 | D (B) | 7-CHLOROTETRACYCLINE | non-polymer | 478.9 | 1 | Chemie (CTC) | |||
| 5 | P, Q (A, B) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A: 196 - 293 (UniProt: P09012)
| PDB | External Database | Details |
|---|---|---|
| His 226 | Tyr 31 | engineered mutation |
| Arg 231 | Gln 36 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32482.3 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 770.5 | |
| All* | Total formula weight | 33252.9 |
