1OPI

SOLUTION STRUCTURE OF THE THIRD RNA RECOGNITION MOTIF (RRM) OF U2AF65 IN COMPLEX WITH AN N-TERMINAL SF1 PEPTIDE

Summary for 1OPI

• Entry DOI: 10.2210/pdb1opi/pdb
• Related: 1O0P
• Descriptor: SPLICING FACTOR U2AF 65 KDA SUBUNIT, SPLICING FACTOR SF1 (2 entities in total)
• Functional Keywords: non-canonical rna recognition motif, 4-stranded anti-parallel beta-sheet, 2 alpha helices additionally extended by a third helix c, rna binding protein
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P26368 Q15637
• Total number of polymer chains: 2
• Total formula weight: 13668.55

Authors

Selenko, P.,Gregorovic, G.,Sprangers, R.,Stier, G.,Rhani, Z.,Kramer, A.,Sattler, M. (deposition date: 2003-03-05, release date: 2004-03-16, Last modification date: 2022-02-23)

• Primary citation: Selenko, P.,Gregorovic, G.,Sprangers, R.,Stier, G.,Rhani, Z.,Kramer, A.,Sattler, M.; Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP; Mol.Cell, 11:965-976, 2003; PubMed: 12718882; DOI: 10.1016/S1097-2765(03)00115-1

Experimental method

SOLUTION NMR