1O0P
Solution Structure of the third RNA Recognition Motif (RRM) of U2AF65 in complex with an N-terminal SF1 peptide
Summary for 1O0P
Entry DOI | 10.2210/pdb1o0p/pdb |
Descriptor | Splicing factor U2AF 65 kDa subunit, Splicing Factor SF1 (2 entities in total) |
Functional Keywords | non-canonical rna recognition motif, 4-stranded anti-parallel beta-sheet, 2 alpha helices additionally extended by a third helix c, rna binding protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P26368 |
Total number of polymer chains | 2 |
Total formula weight | 13668.55 |
Authors | Selenko, P.,Gregorovic, G.,Sprangers, R.,Stier, G.,Rhani, Z.,Kramer, A.,Sattler, M. (deposition date: 2003-02-24, release date: 2003-05-06, Last modification date: 2022-02-23) |
Primary citation | Selenko, P.,Gregorovic, G.,Sprangers, R.,Stier, G.,Rhani, Z.,Kramer, A.,Sattler, M. Structural Basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP Mol.Cell, 11:965-976, 2003 Cited by PubMed: 12718882DOI: 10.1016/S1097-2765(03)00115-1 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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