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1HI6
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BU of 1hi6 by Molmil
ANTI-P24 (HIV-1) FAB FRAGMENT CB41 COMPLEXED WITH A PEPTIDE
Descriptor: IGG2A KAPPA ANTIBODY CB41 (HEAVY CHAIN), IGG2A KAPPA ANTIBODY CB41 (LIGHT CHAIN), PEPTIDE 5
Authors:Hahn, M, Wessner, H, Schneider-Mergener, J, Hohne, W.
Deposit date:2001-01-02
Release date:2001-02-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystallographic Analysis of Anti-P24 (HIV-1) Monoclonal Antibody Cross-Reactivity and Polyspecificity
Cell(Cambridge,Mass.), 91, 1997
1OAR
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BU of 1oar by Molmil
Fv IgE SPE-7 in complex with Alizarin Red
Descriptor: 1,2-ETHANEDIOL, ALIZARIN RED, CACODYLATE ION, ...
Authors:James, L.C, Roversi, P, Tawfik, D.
Deposit date:2003-01-21
Release date:2004-01-15
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
5UAB
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BU of 5uab by Molmil
MET Tyrosine Kinase Inhibition Enhances the Antitumor Efficacy of an HGF Antibody
Descriptor: CHLORIDE ION, GLYCEROL, Hepatocyte growth factor receptor, ...
Authors:Hoffman, I.D, Lawson, J.D.
Deposit date:2016-12-19
Release date:2017-05-31
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:MET Tyrosine Kinase Inhibition Enhances the Antitumor Efficacy of an HGF Antibody.
Mol. Cancer Ther., 16, 2017
1OAU
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BU of 1oau by Molmil
Fv Structure of the IgE SPE-7 in complex with DNP-Ser (immunising hapten)
Descriptor: 2,4-DINITROPHENOL, IMIDAZOLE, IMMUNOGLOBULIN E, ...
Authors:James, L.C, Roversi, P, Tawfik, D.
Deposit date:2003-01-21
Release date:2004-01-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
4POY
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BU of 4poy by Molmil
Engineered Dual Specific VHH antibody
Descriptor: VHH-metal
Authors:Fanning, S.W, Walter, R, Horn, J.R.
Deposit date:2014-02-26
Release date:2014-09-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site.
Protein Eng.Des.Sel., 27, 2014
3I2C
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BU of 3i2c by Molmil
Crystal structure of anti-IL-23 antibody CNTO4088
Descriptor: CNTO4088 HEAVY CHAIN, CNTO4088 LIGHT CHAIN, GLYCEROL
Authors:Teplyakov, A, Obmolova, G, Gilliland, G.L.
Deposit date:2009-06-29
Release date:2009-07-07
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Noncanonical conformation of CDR L1 in the anti-IL-23 antibody CNTO4088.
Acta Crystallogr.,Sect.F, 66, 2010
3GBN
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BU of 3gbn by Molmil
Crystal Structure of Fab CR6261 in Complex with the 1918 H1N1 influenza virus hemagglutinin
Descriptor: 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ekiert, D.C, Elsliger, M.A, Wilson, I.A.
Deposit date:2009-02-20
Release date:2009-03-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antibody recognition of a highly conserved influenza virus epitope.
Science, 324, 2009
4N8C
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BU of 4n8c by Molmil
Three-dimensional structure of the extracellular domain of Matrix protein 2 of influenza A virus
Descriptor: Extracellular domain of influenza Matrix protein 2, Heavy chain of monoclonal antibody, Light chain of monoclonal antibody
Authors:Cho, K.J, Seok, J.H, Kim, S, Roose, K, Schepens, B, Fiers, W, Saelens, X, Kim, K.H.
Deposit date:2013-10-17
Release date:2014-10-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the extracellular domain of matrix protein 2 of influenza A virus in complex with a protective monoclonal antibody
J.Virol., 89, 2015
7LAB
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BU of 7lab by Molmil
Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1052
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1052 heavy chain, ...
Authors:Manne, K, Acharya, P.
Deposit date:2021-01-06
Release date:2021-03-10
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies.
Cell, 184, 2021
6SF6
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BU of 6sf6 by Molmil
Crystal structure of the mAb 15A in complex with COMP-epitope P6
Descriptor: COMP-reactive monoclonal antibody 15A Fab fragment, heavy chain, light chain, ...
Authors:Dobritzsch, D, Ge, C, Holmdahl, R.
Deposit date:2019-08-01
Release date:2020-06-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Antibodies to cartilage oligomeric matrix protein in vivo are pathogenic and clinically relevant in rheumatoid arthritis
To Be Published
8DF1
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BU of 8df1 by Molmil
Chi3l1 bound by antibody C59
Descriptor: C59 Fab Heavy chain, C59 Fab Light chain, Chitinase-3-like protein 1, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2022-06-21
Release date:2023-03-01
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice.
Antib Ther, 6, 2023
3IXY
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BU of 3ixy by Molmil
The pseudo-atomic structure of dengue immature virus in complex with Fab fragments of the anti-fusion loop antibody E53
Descriptor: E53 Fab Fragment (chain H), E53 Fab Fragment (chain L), Envelope protein E, ...
Authors:Cherrier, M.V, Kaufmann, B, Nybakken, G.E, Lok, S.M, Warren, J.T, Nelson, C.A, Kostyuchenko, V.A, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Diamond, M.S, Rossmann, M.G, Fremont, D.H.
Deposit date:2009-02-26
Release date:2009-10-27
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody
Embo J., 28, 2009
4Q9B
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BU of 4q9b by Molmil
IgNAR antibody domain C2
Descriptor: Novel antigen receptor
Authors:Feige, J.M, Graewert, M.A, Marcinowski, M, Hennig, J, Behnke, J, Auslaender, D, Herold, E.M, Peschek, J, Castro, C.D, Flajnik, M.F, Hendershot, L.M, Sattler, M, Groll, M, Buchner, J.
Deposit date:2014-04-30
Release date:2014-07-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
Proc.Natl.Acad.Sci.USA, 111, 2014
3IXX
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BU of 3ixx by Molmil
The pseudo-atomic structure of West Nile immature virus in complex with Fab fragments of the anti-fusion loop antibody E53
Descriptor: E53 Fab Fragment (chain H), E53 Fab Fragment (chain L), Envelope protein E, ...
Authors:Cherrier, M.V, Kaufmann, B, Nybakken, G.E, Lok, S.M, Warren, J.T, Nelson, C.A, Kostyuchenko, V.A, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Diamond, M.S, Rossmann, M.G, Fremont, D.H.
Deposit date:2009-02-26
Release date:2009-10-27
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody
Embo J., 28, 2009
4Q9C
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BU of 4q9c by Molmil
IgNAR antibody domain C3
Descriptor: CHLORIDE ION, Novel antigen receptor, SODIUM ION, ...
Authors:Feige, J.M, Graewert, M.A, Marcinowski, M, Hennig, J, Behnke, J, Auslaender, D, Herold, E.M, Peschek, J, Castro, C.D, Flajnik, M.F, Hendershot, L.M, Sattler, M, Groll, M, Buchner, J.
Deposit date:2014-04-30
Release date:2014-07-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
Proc.Natl.Acad.Sci.USA, 111, 2014
7LD1
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BU of 7ld1 by Molmil
Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1047
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 heavy chain, ...
Authors:Manne, K, Acharya, P.
Deposit date:2021-01-12
Release date:2021-01-27
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies.
Cell, 184, 2021
7T2P
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BU of 7t2p by Molmil
The Envelope Glycoprotein SIVmac239.K180S SOSIP trimer in complex with 3 copies of the neutralizing antibody K11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Berndsen, Z.T, Ward, A.B.
Deposit date:2021-12-06
Release date:2022-10-19
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus.
Nat Commun, 13, 2022
7T4G
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BU of 7t4g by Molmil
The Envelope Glycoprotein SIVmac239.K180S SOSIP trimer in complex with 3 copies of the neutralizing antibody K11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Berndsen, Z.T, Ward, A.B.
Deposit date:2021-12-09
Release date:2022-10-19
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus.
Nat Commun, 13, 2022
5GZR
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BU of 5gzr by Molmil
Zika virus E protein complexed with a neutralizing antibody Z23-Fab
Descriptor: Z23 Fab heavy chain, Z23 Fab light chain, structural protein E, ...
Authors:Gao, G.G, Shi, Y, Peng, R, Liu, S.
Deposit date:2016-10-01
Release date:2016-11-30
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
6X87
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BU of 6x87 by Molmil
CryoEM structure of the Plasmodium berghei circumsporozoite protein in complex with inhibitory mouse antibody 3D11.
Descriptor: 3D11 Fab heavy chain, 3D11 Fab kappa chain, Circumsporozoite protein
Authors:Kucharska, I, Thai, E, Rubinstein, J, Julien, J.P.
Deposit date:2020-06-01
Release date:2020-12-02
Last modified:2020-12-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11.
Elife, 9, 2020
5DO2
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BU of 5do2 by Molmil
Complex structure of MERS-RBD bound with 4C2 antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4C2 heavy chain, 4C2 light chain, ...
Authors:Li, Y, Wan, Y, Liu, P, Zhao, J, Lu, G, Qi, J, Wang, Q, Lu, X, Wu, Y, Liu, W, Yuen, K.Y, Perlman, S, Gao, G.F, Yan, J.
Deposit date:2015-09-10
Release date:2015-10-14
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.409 Å)
Cite:A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein.
Cell Res., 25, 2015
5DUP
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BU of 5dup by Molmil
Influenza A virus H5 hemagglutinin globular head in complex with antibody AVFluIgG03
Descriptor: AVFluIgG03 Heavy Chain, AVFluIgG03 Light Chain, Hemagglutinin
Authors:Zuo, T, Sun, J, Wang, G, Zhou, P, Wang, X, Zhang, L.
Deposit date:2015-09-20
Release date:2015-12-16
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.052 Å)
Cite:Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection
Nat Commun, 6, 2015
5DUM
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BU of 5dum by Molmil
Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody 65C6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 65C6 Heavy Chain, 65C6 Light Chain, ...
Authors:Sun, J, Zuo, T, Wang, G, Zhou, P, Zhang, L, Wang, X.
Deposit date:2015-09-19
Release date:2015-12-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection
Nat Commun, 6, 2015
5BVJ
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BU of 5bvj by Molmil
The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1beta
Descriptor: canakinumab Fab heavy-chain, canakinumab Fab light-chain
Authors:Rondeau, J.M.
Deposit date:2015-06-05
Release date:2015-09-02
Last modified:2020-03-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1 beta.
Mabs, 7, 2015
5BVP
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BU of 5bvp by Molmil
The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1beta
Descriptor: CHLORIDE ION, Canakinumab Fab light-chain, Interleukin-1 beta, ...
Authors:Rondeau, J.M.
Deposit date:2015-06-05
Release date:2015-09-02
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1 beta.
Mabs, 7, 2015

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