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7FDX	X-ray structure of the human heart fatty acid-binding protein complexed with the fluorescent probe 8-Anilino-1-naphthalenesulfonic acid (ANS) Descriptor: 8-ANILINO-1-NAPHTHALENE SULFONATE, Fatty acid-binding protein, heart Authors: Sugiyama, S, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M. Deposit date: 2021-07-18 Release date: 2022-07-20 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (0.95 Å) Cite: X-ray structure of the human heart fatty acid-binding protein complexed with the fluorescent probe 8-Anilino-1-naphthalenesulfonic acid (ANS) To Be Published
7FEU	The 0.95 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with perfluorononanoic acid Descriptor: Fatty acid-binding protein, heart, HEXAETHYLENE GLYCOL, ... Authors: Sugiyama, S, Kakinouchi, K, Hara, T, Nakano, R, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M. Deposit date: 2021-07-21 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (0.95 Å) Cite: The 0.95 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with perfluorononanoic acid To Be Published
7FDU	The 0.86 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with heptadecanoic acid Descriptor: Fatty acid-binding protein, heart, HEXAETHYLENE GLYCOL, ... Authors: Sugiyama, S, Kakinouchi, K, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M. Deposit date: 2021-07-18 Release date: 2022-07-20 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (0.86 Å) Cite: The 0.86 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with heptadecanoic acid To Be Published
7FEZ	The 0.76 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with petroselinic acid Descriptor: Fatty acid-binding protein, heart, PENTAETHYLENE GLYCOL, ... Authors: Sugiyama, S, Kakinouchi, K, Nakano, R, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M. Deposit date: 2021-07-22 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (0.76 Å) Cite: The 0.76 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with petroselinic acid To Be Published
7FFK	The 0.84 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with palmitoleic acid Descriptor: Fatty acid-binding protein, heart, HEXAETHYLENE GLYCOL, ... Authors: Sugiyama, S, Kakinouchi, K, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M. Deposit date: 2021-07-23 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (0.84 Å) Cite: The 0.84 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with palmitoleic acid To Be Published
7FF6	The 0.83 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with cis-vaccenic acid Descriptor: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, Fatty acid-binding protein, heart, ... Authors: Sugiyama, S, Kakinouchi, K, Nakano, R, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M. Deposit date: 2021-07-22 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (0.83 Å) Cite: The 0.83 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with cis-vaccenic acid To Be Published
7FEK	The 1.05 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with perfluorooctanoic acid Descriptor: DI(HYDROXYETHYL)ETHER, Fatty acid-binding protein, heart, ... Authors: Sugiyama, S, Kakinouchi, K, Hara, T, Nakano, R, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M. Deposit date: 2021-07-21 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.05 Å) Cite: The 1.05 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with perfluorooctanoic acid To Be Published
7FFX	The 0.88 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with alpha-llinolenic acid Descriptor: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, ALPHA-LINOLENIC ACID, Fatty acid-binding protein, ... Authors: Sugiyama, S, Nakano, R, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M. Deposit date: 2021-07-24 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (0.88 Å) Cite: The 0.88 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with alpha-llinolenic acid To Be Published
7FG1	The 0.93 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with tridecanoic acid Descriptor: Fatty acid-binding protein, heart, HEXAETHYLENE GLYCOL, ... Authors: Sugiyama, S, Takahashi, J, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M. Deposit date: 2021-07-25 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (0.93 Å) Cite: The 0.93 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with tridecanoic acid To Be Published
7FG5	Room temperature structure of the human heart fatty acid-binding protein complexed with capric acid Descriptor: DECANOIC ACID, Fatty acid-binding protein, heart Authors: Sugiyama, S, Kakinouchi, K, Takahashi, J, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M. Deposit date: 2021-07-26 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Room temperature structure of the human heart fatty acid-binding protein complexed with capric acid To Be Published
2RD7	Human Complement Membrane Attack Proteins Share a Common Fold with Bacterial Cytolysins Descriptor: CHLORIDE ION, Complement component C8 alpha chain, Complement component C8 gamma chain Authors: Slade, D.J, Lovelace, L.L, Chruszcz, M, Minor, W, Lebioda, L, Sodetz, J.M. Deposit date: 2007-09-21 Release date: 2008-05-27 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement. J. Biol. Chem., 286, 2011
6QBA	Crystal Structure of Retinol-Binding Protein 4 (RBP4) in complex with non-retinoid ligand A1120 and engineered binding scaffold Descriptor: 2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Mlynek, G, Brey, C.U, Djinovic-Carugo, K, Puehringer, D. Deposit date: 2018-12-20 Release date: 2020-06-03 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A conformation-specific ON-switch for controlling CAR T cells with an orally available drug. Proc.Natl.Acad.Sci.USA, 117, 2020
2WQA	Complex of TTR and RBP4 and Oleic Acid Descriptor: OLEIC ACID, RETINOL-BINDING PROTEIN 4, SULFATE ION, ... Authors: Nanao, M, Mercer, D, Nguyen, L, Buckley, D, Stout, T.J. Deposit date: 2009-08-14 Release date: 2010-09-01 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Crystal Structure of Rbp4 Bound to Linoleic Acid and Ttr To be Published
6S8V	Structure of the high affinity Anticalin P3D11 in complex with the human CD98 heavy chain ectodomain Descriptor: 1,2-ETHANEDIOL, 4F2 cell-surface antigen heavy chain, Neutrophil gelatinase-associated lipocalin Authors: Schiefner, A, Deuschle, F.-C, Skerra, A. Deposit date: 2019-07-10 Release date: 2020-03-04 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Development of a high affinity Anticalin®directed against human CD98hc for theranostic applications. Theranostics, 10, 2020
6SUA	Structure of the high affinity engineered lipocalin C1B12 in complex with the mouse CD98 heavy chain ectodomain Descriptor: 4F2 cell-surface antigen heavy chain, Neutrophil gelatinase-associated lipocalin, SULFATE ION Authors: Schiefner, A, Deuschle, F.-C, Skerra, A. Deposit date: 2019-09-13 Release date: 2020-06-17 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Design of a surrogate Anticalin protein directed against CD98hc for preclinical studies in mice. Protein Sci., 29, 2020
1RLB	RETINOL BINDING PROTEIN COMPLEXED WITH TRANSTHYRETIN Descriptor: RETINOIC ACID, RETINOL BINDING PROTEIN, TRANSTHYRETIN Authors: Monaco, H.L, Rizzi, M, Coda, A. Deposit date: 1995-02-20 Release date: 1996-04-11 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structure of a complex of two plasma proteins: transthyretin and retinol-binding protein. Science, 268, 1995
3BSZ	Crystal structure of the transthyretin-retinol binding protein-Fab complex Descriptor: Fab fragment heavy chain, Fab fragment light chain, Plasma retinol-binding protein, ... Authors: Zanotti, G, Cendron, L, Gliubich, F, Folli, C, Berni, R. Deposit date: 2007-12-27 Release date: 2008-11-11 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.38 Å) Cite: Structural and mutational analyses of protein-protein interactions between transthyretin and retinol-binding protein. Febs J., 275, 2008
1QAB	The structure of human retinol binding protein with its carrier protein transthyretin reveals interaction with the carboxy terminus of RBP Descriptor: PROTEIN (retinol binding protein), PROTEIN (transthyretin), RETINOL Authors: Naylor, H.M, Newcomer, M.E. Deposit date: 1999-02-03 Release date: 1999-02-16 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.2 Å) Cite: The structure of human retinol-binding protein (RBP) with its carrier protein transthyretin reveals an interaction with the carboxy terminus of RBP. Biochemistry, 38, 1999
4QAF	Crystal structure of an engineered lipocalin (Anticalin) in complex with VEGF(8-109) Descriptor: 10-{(1R,2R)-2-[(2E)-hex-2-en-1-yl]cyclopropyl}decanoic acid, ACETATE ION, Lipocalin-1, ... Authors: Giese, T, Skerra, A. Deposit date: 2014-05-04 Release date: 2015-05-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of an Anticalin with specific blocking activity towards human vascular endothelial growth factor (VEGF) reveals plasticity of the lipocalin fold To be Published
4QAE	Crystal structure of an engineered lipocalin (Anticalin) in complex with human hepcidin Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Hepcidin, ... Authors: Giese, T, Skerra, A. Deposit date: 2014-05-04 Release date: 2015-05-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of a hepcidin-binding anticalin in complex with its peptide ligand To be Published
4MVL	Crystal structure of an engineered lipocalin (Anticalin H1GA) in complex with the Alzheimer amyloid peptide Abeta1-40 Descriptor: Beta-amyloid protein 40, Neutrophil gelatinase-associated lipocalin Authors: Eichinger, A, Skerra, A. Deposit date: 2013-09-24 Release date: 2015-08-12 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide. Biochem.J., 473, 2016
4MVI	Crystal structure of an engineered lipocalin (Anticalin US7) in complex with the Alzheimer amyloid peptide Abeta(1-40) Descriptor: Beta-amyloid protein 40, Neutrophil gelatinase-associated lipocalin Authors: Eichinger, A, Skerra, A. Deposit date: 2013-09-24 Release date: 2015-08-12 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide. Biochem.J., 473, 2016
4GH7	Crystal structure of Anticalin N7A in complex with oncofetal fibronectin fragment Fn7B8 Descriptor: Fibronectin, Neutrophil gelatinase-associated lipocalin Authors: Schiefner, A, Gebauer, M, Skerra, A. Deposit date: 2012-08-07 Release date: 2012-12-26 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Combinatorial design of an Anticalin directed against the extra-domain b for the specific targeting of oncofetal fibronectin J.Mol.Biol., 425, 2013
8B0H	2C9, C5b9-CD59 cryoEM structure Descriptor: CD59 glycoprotein, Complement C5, Complement component C6, ... Authors: Couves, E.C, Gardner, S, Bubeck, D. Deposit date: 2022-09-07 Release date: 2023-02-22 Last modified: 2023-03-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis for membrane attack complex inhibition by CD59. Nat Commun, 14, 2023
8B0F	CryoEM structure of C5b8-CD59 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Bubeck, D, Couves, E.C, Gardner, S. Deposit date: 2022-09-07 Release date: 2023-02-22 Last modified: 2023-03-01 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis for membrane attack complex inhibition by CD59. Nat Commun, 14, 2023

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