4QAE

Crystal structure of an engineered lipocalin (Anticalin) in complex with human hepcidin

Summary for 4QAE

• Entry DOI: 10.2210/pdb4qae/pdb
• Descriptor: Hepcidin, Neutrophil gelatinase-associated lipocalin, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: beta-barrel, engineered lipocalin, binding protein, protein-peptide complex, transport protein-signaling protein complex, transport protein/signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted : P81172 P80188
• Total number of polymer chains: 12
• Total formula weight: 146921.59

Authors

Giese, T.,Skerra, A. (deposition date: 2014-05-04, release date: 2015-05-06, Last modification date: 2024-11-06)

• Primary citation: Giese, T.,Skerra, A.; Structure of a hepcidin-binding anticalin in complex with its peptide ligand; To be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)