6S8V
Structure of the high affinity Anticalin P3D11 in complex with the human CD98 heavy chain ectodomain
Summary for 6S8V
Entry DOI | 10.2210/pdb6s8v/pdb |
Descriptor | Neutrophil gelatinase-associated lipocalin, 4F2 cell-surface antigen heavy chain, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | lipocalin, lcn2, anticalin, lipocalin-based binding protein, cd98hc, 4f2hc, amino acid transport, presentation of cd98 light chains, interaction with integrin beta subunits, single-pass type ii membrane protein, protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 137420.47 |
Authors | Schiefner, A.,Deuschle, F.-C.,Skerra, A. (deposition date: 2019-07-10, release date: 2020-03-04, Last modification date: 2024-01-24) |
Primary citation | Deuschle, F.C.,Morath, V.,Schiefner, A.,Brandt, C.,Ballke, S.,Reder, S.,Steiger, K.,Schwaiger, M.,Weber, W.,Skerra, A. Development of a high affinity Anticalin®directed against human CD98hc for theranostic applications. Theranostics, 10:2172-2187, 2020 Cited by PubMed: 32089738DOI: 10.7150/thno.38968 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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