1ZVV
 
 | | Crystal structure of a ccpa-crh-dna complex | | Descriptor: | DNA recognition strand CRE, Glucose-resistance amylase regulator, HPr-like protein crh, ... | | Authors: | Schumacher, M.A, Brennan, R.G, Hillen, W, Seidel, G. | | Deposit date: | 2005-06-02 | | Release date: | 2006-02-07 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.98 Å) | | Cite: | Phosphoprotein Crh-Ser46-P displays altered binding to CcpA to effect carbon catabolite regulation.
J.Biol.Chem., 281, 2006
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4HJ9
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4HIO
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4HIM
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8R0S
 | | Structure of reverse transcriptase from Cauliflower Mosaic Virus in complex with RNA/DNA hybrid | | Descriptor: | DNA (5'-D(*GP*CP*TP*AP*CP*GP*CP*AP*CP*TP*GP*CP*TP*GP*GP*A)-3'), Enzymatic polyprotein, RNA (5'-R(*GP*UP*CP*CP*AP*GP*CP*AP*GP*UP*GP*CP*GP*UP*AP*GP*C)-3') | | Authors: | Prabaharan, C, Figiel, M, Chamera, S, Szczepanowski, R, Nowak, E, Nowotny, M. | | Deposit date: | 2023-10-31 | | Release date: | 2024-07-24 | | Last modified: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural and biochemical characterization of cauliflower mosaic virus reverse transcriptase.
J.Biol.Chem., 300, 2024
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8GKH
 | | Structure of the Spizellomyces punctatus Fanzor (SpuFz) in complex with omega RNA and target DNA | | Descriptor: | DNA (35-MER), DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), MAGNESIUM ION, ... | | Authors: | Xu, P, Saito, M, Zhang, F. | | Deposit date: | 2023-03-19 | | Release date: | 2023-07-05 | | Last modified: | 2023-08-30 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Fanzor is a eukaryotic programmable RNA-guided endonuclease.
Nature, 620, 2023
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8GN4
 | | The crystal structure of ZBTB10 ZF1-2 R767Q in complex with telomeric DNA TTAGGG | | Descriptor: | DNA (5'-D(*AP*TP*AP*TP*AP*AP*CP*CP*CP*TP*A)-3'), DNA (5'-D(*TP*TP*AP*GP*GP*GP*TP*TP*AP*TP*A)-3'), ZINC ION, ... | | Authors: | Li, F.D, Wang, S.M. | | Deposit date: | 2022-08-22 | | Release date: | 2023-08-30 | | Last modified: | 2024-04-24 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural insights into the recognition of telomeric variant repeat TTGGGG by broad-complex, tramtrack and bric-a-brac - zinc finger protein ZBTB10.
J.Biol.Chem., 299, 2023
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7DVV
 | | Heme sensor protein PefR from Streptococcus agalactiae bound to operator DNA (28-mer) | | Descriptor: | DNA (28-MER), HTH marR-type domain-containing protein | | Authors: | Nishinaga, M, Nagai, S, Nishitani, Y, Sugimoto, H, Shiro, Y, Sawai, H. | | Deposit date: | 2021-01-15 | | Release date: | 2021-09-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Heme controls the structural rearrangement of its sensor protein mediating the hemolytic bacterial survival.
Commun Biol, 4, 2021
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8WMN
 | | Structure of CbCas9-PcrIIC1 complex bound to 62-bp DNA substrate (symmetric 20-nt complementary) | | Descriptor: | DNA (62-MER), MAGNESIUM ION, PcrIIC1, ... | | Authors: | Zhang, S, Lin, S, Liu, J.J.G. | | Deposit date: | 2023-10-04 | | Release date: | 2024-06-05 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (2.82 Å) | | Cite: | Pro-CRISPR PcrIIC1-associated Cas9 system for enhanced bacterial immunity.
Nature, 630, 2024
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6W7A
 | | The crystal structure of the 2009/H1N1/California PA endonuclease mutant E119D bound to DNA oligomer TAGCAT (uncleaved, 5mM overnight DNA soak) | | Descriptor: | DNA (5'-D(P*TP*AP*GP*CP*AP*T)-3'), GLYCEROL, MANGANESE (II) ION, ... | | Authors: | Cuypers, M.G, Kumar, G, Webb, T, White, S.W. | | Deposit date: | 2020-03-18 | | Release date: | 2021-02-03 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Structural insights into the substrate specificity of the endonuclease activity of the influenza virus cap-snatching mechanism.
Nucleic Acids Res., 49, 2021
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8WH0
 | | MPOX E5 hexamer ssDNA and AMP-PNP bound conformation | | Descriptor: | DNA (5'-D(P*CP*CP*CP*CP*C)-3'), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Zhang, Z, Dong, C. | | Deposit date: | 2023-09-22 | | Release date: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (2.51 Å) | | Cite: | Essential and multifunctional mpox virus E5 helicase-primase in double and single hexamer.
Sci Adv, 10, 2024
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5HRO
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1A1V
 | | HEPATITIS C VIRUS NS3 HELICASE DOMAIN COMPLEXED WITH SINGLE STRANDED SDNA | | Descriptor: | DNA (5'-D(*UP*UP*UP*UP*UP*UP*UP*U)-3'), PROTEIN (NS3 PROTEIN), SULFATE ION | | Authors: | Kim, J.L, Morgenstern, K.A, Griffith, J.P, Dwyer, M.D, Thomson, J.A, Murcko, M.A, Lin, C, Caron, P.R. | | Deposit date: | 1997-12-17 | | Release date: | 1999-01-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding.
Structure, 6, 1998
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8HWH
 | | Cryo-EM Structure of D5 Apo-ssDNA form | | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), Primase D5 | | Authors: | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | | Deposit date: | 2022-12-29 | | Release date: | 2024-01-10 | | Last modified: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
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1LCC
 | | STRUCTURE OF THE COMPLEX OF LAC REPRESSOR HEADPIECE AND AN 11 BASE-PAIR HALF-OPERATOR DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND RESTRAINED MOLECULAR DYNAMICS | | Descriptor: | DNA (5'-D(*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), Lac Repressor, ... | | Authors: | Chuprina, V.P, Rullmann, J.A.C, Lamerichs, R.M.J.N, Van Boom, J.H, Boelens, R, Kaptein, R. | | Deposit date: | 1993-03-25 | | Release date: | 1994-01-31 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics.
J.Mol.Biol., 234, 1993
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2HIK
 | | heterotrimeric PCNA sliding clamp | | Descriptor: | PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405) | | Authors: | Pascal, J.M, Tsodikov, O.V, Ellenberger, T. | | Deposit date: | 2006-06-29 | | Release date: | 2006-11-07 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA.
Mol.Cell, 24, 2006
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2HII
 | | heterotrimeric PCNA sliding clamp | | Descriptor: | PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405) | | Authors: | Pascal, J.M, Tsodikov, O.V, Ellenberger, T. | | Deposit date: | 2006-06-29 | | Release date: | 2006-11-07 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA.
Mol.Cell, 24, 2006
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2M8Y
 | | Structure of d[CGCGAAGCATTCGCG] hairpin | | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*GP*CP*AP*TP*TP*CP*GP*CP*G)-3') | | Authors: | Lim, K.W, Phan, A.T. | | Deposit date: | 2013-05-30 | | Release date: | 2013-07-10 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural basis of DNA quadruplex-duplex junction formation.
Angew.Chem.Int.Ed.Engl., 52, 2013
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1LCD
 | | STRUCTURE OF THE COMPLEX OF LAC REPRESSOR HEADPIECE AND AN 11 BASE-PAIR HALF-OPERATOR DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND RESTRAINED MOLECULAR DYNAMICS | | Descriptor: | DNA (5'-D(*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), Lac Repressor, ... | | Authors: | Chuprina, V.P, Rullmann, J.A.C, Lamerichs, R.M.J.N, Van Boom, J.H, Boelens, R, Kaptein, R. | | Deposit date: | 1993-03-25 | | Release date: | 1994-01-31 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics.
J.Mol.Biol., 234, 1993
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8BPR
 | | Complex of RecF-RecO-RecR-DNA from Thermus thermophilus (low resolution reconstruction). | | Descriptor: | DNA repair protein RecO, DNA replication and repair protein RecF, MAGNESIUM ION, ... | | Authors: | Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M. | | Deposit date: | 2022-11-17 | | Release date: | 2023-04-26 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination.
Nat.Struct.Mol.Biol., 30, 2023
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8WQ5
 | | Crystal structure of the C-terminal RRM domain of an RBP in complex with ssDNA | | Descriptor: | DNA (5'-D(*GP*AP*CP*GP*CP*AP*G)-3'), GLYCEROL, RNA-binding protein 45 | | Authors: | Chen, X, Yang, Z, Chen, X, Wei, Q, Guo, S, Jiang, M, Wang, M. | | Deposit date: | 2023-10-11 | | Release date: | 2024-08-21 | | Last modified: | 2024-09-18 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structural basis for RNA recognition by the C-terminal RRM domain of human RBM45.
J.Biol.Chem., 300, 2024
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7KSP
 | | Crystal structure of hSAMD9_DBD with DNA | | Descriptor: | DNA, Sterile alpha motif domain-containing protein 9 | | Authors: | Peng, S, Pathak, P, Xiang, Y, Deng, J. | | Deposit date: | 2020-11-23 | | Release date: | 2022-01-05 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure and function of an effector domain in antiviral factors and tumor suppressors SAMD9 and SAMD9L.
Proc.Natl.Acad.Sci.USA, 119, 2022
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2CRX
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8A93
 | | Complex of RecF-RecR-DNA from Thermus thermophilus. | | Descriptor: | DNA replication and repair protein RecF, MAGNESIUM ION, Oligo1, ... | | Authors: | Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M. | | Deposit date: | 2022-06-27 | | Release date: | 2023-04-26 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination.
Nat.Struct.Mol.Biol., 30, 2023
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6ZT4
 | | Pentapeptide repeat protein MfpA from Mycobacterium smegmatis | | Descriptor: | 1,2-ETHANEDIOL, Pentapeptide repeat protein MfpA | | Authors: | Feng, L, Mundy, J.E.A, Stevenson, C.E.M, Mitchenall, L.A, Lawson, D.M, Mi, K, Maxwell, A. | | Deposit date: | 2020-07-17 | | Release date: | 2021-03-03 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | The pentapeptide-repeat protein, MfpA, interacts with mycobacterial DNA gyrase as a DNA T-segment mimic.
Proc.Natl.Acad.Sci.USA, 118, 2021
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