6W7A
The crystal structure of the 2009/H1N1/California PA endonuclease mutant E119D bound to DNA oligomer TAGCAT (uncleaved, 5mM overnight DNA soak)
Summary for 6W7A
Entry DOI | 10.2210/pdb6w7a/pdb |
Related | 6W5P |
Descriptor | Protein PA-X,Polymerase acidic protein, DNA (5'-D(P*TP*AP*GP*CP*AP*T)-3'), GLYCEROL, ... (6 entities in total) |
Functional Keywords | nuclease, influenza, dna oligomer, uncleaved, viral protein, viral protein-dna complex, viral protein/dna |
Biological source | Influenza A virus More |
Total number of polymer chains | 2 |
Total formula weight | 25886.12 |
Authors | Cuypers, M.G.,Kumar, G.,Webb, T.,White, S.W. (deposition date: 2020-03-18, release date: 2021-02-03, Last modification date: 2023-10-25) |
Primary citation | Kumar, G.,Cuypers, M.,Webby, R.R.,Webb, T.R.,White, S.W. Structural insights into the substrate specificity of the endonuclease activity of the influenza virus cap-snatching mechanism. Nucleic Acids Res., 49:1609-1618, 2021 Cited by PubMed: 33469660DOI: 10.1093/nar/gkaa1294 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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