6VXV
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![BU of 6vxv by Molmil](/molmil-images/mine/6vxv) | Crystal structure of cyclo-L-Trp-L-Pro-bound cytochrome P450 NasF5053 from Streptomyces sp. NRRL F-5053 | Descriptor: | (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, CALCIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Luo, Z, Jia, X, Sun, C, Qu, X, Kobe, B. | Deposit date: | 2020-02-24 | Release date: | 2020-11-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines. Nat Commun, 11, 2020
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7ROF
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7RNP
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1WBJ
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![BU of 1wbj by Molmil](/molmil-images/mine/1wbj) | wildtype tryptophan synthase complexed with glycerol phosphate | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, SN-GLYCEROL-3-PHOSPHATE, SODIUM ION, ... | Authors: | Kulik, V, Weyand, M, Schlichting, I. | Deposit date: | 2004-11-01 | Release date: | 2006-05-24 | Last modified: | 2019-05-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | On the Structural Basis of the Catalytic Mechanism and the Regulation of the Alpha Subunit of Tryptophan Synthase from Salmonella Typhimurium and Bx1 from Maize, Two Evolutionarily Related Enzymes. J.Mol.Biol., 352, 2005
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4GIF
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![BU of 4gif by Molmil](/molmil-images/mine/4gif) | C-terminal coiled-coil domain of transient receptor potential channel TRPP3 (PKD2L1, Polycystin-L) | Descriptor: | Polycystic kidney disease 2-like 1 protein | Authors: | Yu, Y, Ulbrich, M.H, Li, M.-H, Dobbins, S, Zhang, W.K, Tong, L, Isacoff, E.Y, Yang, J. | Deposit date: | 2012-08-08 | Release date: | 2012-12-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex. Nat Commun, 3, 2012
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3CVA
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![BU of 3cva by Molmil](/molmil-images/mine/3cva) | Human Bcl-xL containing a Trp to Ala mutation at position 137 | Descriptor: | Apoptosis regulator Bcl-X | Authors: | Feng, Y, Zhang, L, Hu, T, Shen, X, Chen, K, Jiang, H, Liu, D. | Deposit date: | 2008-04-18 | Release date: | 2009-03-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A conserved hydrophobic core at Bcl-x(L) mediates its structural stability and binding affinity with BH3-domain peptide of pro-apoptotic protein Arch.Biochem.Biophys., 484, 2009
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1YI8
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2VYY
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![BU of 2vyy by Molmil](/molmil-images/mine/2vyy) | Mutant Ala55Trp of Cerebratuls lacteus mini-hemoglobin | Descriptor: | GLYCEROL, NEURAL HEMOGLOBIN, OXYGEN MOLECULE, ... | Authors: | Salter, M.D, Nienhaus, K, Nienhaus, G.U, Dewilde, S, Moens, L, Pesce, A, Nardini, M, Bolognesi, M, Olson, J.S. | Deposit date: | 2008-07-29 | Release date: | 2008-10-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The Apolar Channel in Cerebratulus Lacteus Hemoglobin is the Route for O2 Entry and Exit. J.Biol.Chem., 283, 2008
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4E8D
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![BU of 4e8d by Molmil](/molmil-images/mine/4e8d) | Crystal structure of streptococcal beta-galactosidase | Descriptor: | GLYCEROL, Glycosyl hydrolase, family 35 | Authors: | Cheng, W, Wang, L, Bai, X.H, Jiang, Y.L, Li, Q, Yu, G, Zhou, C.Z, Chen, Y.X. | Deposit date: | 2012-03-20 | Release date: | 2012-05-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into the substrate specificity of Streptococcus pneumoniae beta (1,3)-galactosidase BgaC J.Biol.Chem., 287, 2012
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4E8C
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![BU of 4e8c by Molmil](/molmil-images/mine/4e8c) | Crystal structure of streptococcal beta-galactosidase in complex with galactose | Descriptor: | GLYCEROL, Glycosyl hydrolase, family 35, ... | Authors: | Cheng, W, Wang, L, Bai, X.H, Jiang, Y.L, Li, Q, Yu, G, Zhou, C.Z, Chen, Y.X. | Deposit date: | 2012-03-20 | Release date: | 2012-05-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural insights into the substrate specificity of Streptococcus pneumoniae beta (1,3)-galactosidase BgaC J.Biol.Chem., 287, 2012
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4PKW
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![BU of 4pkw by Molmil](/molmil-images/mine/4pkw) | Anthrax toxin lethal factor with bound small molecule inhibitor GM6001 | Descriptor: | 1,2-ETHANEDIOL, 3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE, GLYCEROL, ... | Authors: | Maize, K.M, De la Mora, T, Finzel, B.C. | Deposit date: | 2014-05-15 | Release date: | 2014-11-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Anthrax toxin lethal factor domain 3 is highly mobile and responsive to ligand binding. Acta Crystallogr.,Sect.D, 70, 2014
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6HUL
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![BU of 6hul by Molmil](/molmil-images/mine/6hul) | Sulfolobus solfataricus Tryptophan Synthase AB Complex | Descriptor: | PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, SERINE, ... | Authors: | Fleming, J.R, Mayans, O. | Deposit date: | 2018-10-08 | Release date: | 2018-11-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Evolutionary Morphing of Tryptophan Synthase: Functional Mechanisms for the Enzymatic Channeling of Indole. J.Mol.Biol., 430, 2018
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2O5Y
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2O5X
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2O5Z
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2DH6
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![BU of 2dh6 by Molmil](/molmil-images/mine/2dh6) | Crystal structure of E. coli Apo-TrpB | Descriptor: | SULFATE ION, tryptophan synthase beta subunit | Authors: | Nishio, K, Morimoto, Y, Ogasahara, K, Yasuoka, N, Yutani, K, Tsukihara, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-03-23 | Release date: | 2007-04-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Large conformational changes in the Escherichia coli tryptophan synthase beta(2) subunit upon pyridoxal 5'-phosphate binding Febs J., 277, 2010
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2DH5
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![BU of 2dh5 by Molmil](/molmil-images/mine/2dh5) | Crystal structure of E. coli Holo-TrpB | Descriptor: | GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION, ... | Authors: | Nishio, K, Morimoto, Y, Ogasahara, K, Yutani, K, Tsukihara, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-03-23 | Release date: | 2007-04-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Large conformational changes in the Escherichia coli tryptophan synthase beta(2) subunit upon pyridoxal 5'-phosphate binding Febs J., 277, 2010
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5KIN
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![BU of 5kin by Molmil](/molmil-images/mine/5kin) | Crystal structure of tryptophan synthase alpha beta complex from Streptococcus pneumoniae | Descriptor: | GLYCEROL, Tryptophan synthase alpha chain, Tryptophan synthase beta chain | Authors: | Chang, C, Michalska, K, Bigelow, L, Jedrzejczak, R, ANDERSON, W.F, JOACHIMIAK, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-06-16 | Release date: | 2016-07-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Conservation of the structure and function of bacterial tryptophan synthases. Iucrj, 6, 2019
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3UFZ
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![BU of 3ufz by Molmil](/molmil-images/mine/3ufz) | Crystal structure of a Trp-less green fluorescent protein translated by the universal genetic code | Descriptor: | Green fluorescent protein | Authors: | Kawahara-Kobayashi, A, Araiso, Y, Matsuda, T, Yokoyama, S, Kigawa, T, Nureki, O, Kiga, D. | Deposit date: | 2011-11-02 | Release date: | 2012-10-17 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Simplification of the genetic code: restricted diversity of genetically encoded amino acids. Nucleic Acids Res., 40, 2012
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5DW3
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3UG0
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![BU of 3ug0 by Molmil](/molmil-images/mine/3ug0) | Crystal structure of a Trp-less green fluorescent protein translated by the simplified genetic code | Descriptor: | Green fluorescent protein | Authors: | Kawahara-Kobayashi, A, Araiso, Y, Matsuda, T, Yokoyama, S, Kigawa, T, Nureki, O, Kiga, D. | Deposit date: | 2011-11-02 | Release date: | 2012-10-17 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.093 Å) | Cite: | Simplification of the genetic code: restricted diversity of genetically encoded amino acids. Nucleic Acids Res., 40, 2012
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5KZM
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![BU of 5kzm by Molmil](/molmil-images/mine/5kzm) | Crystal structure of Tryptophan synthase alpha-beta chain complex from Francisella tularensis | Descriptor: | ACETATE ION, CALCIUM ION, Tryptophan synthase alpha chain, ... | Authors: | Chang, C, Michalska, K, Joachimiak, G, Jedrzejczak, R, ANDERSON, W.F, JOACHIMIAK, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-07-25 | Release date: | 2016-08-10 | Last modified: | 2019-09-18 | Method: | X-RAY DIFFRACTION (2.804 Å) | Cite: | Conservation of the structure and function of bacterial tryptophan synthases. Iucrj, 6, 2019
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7ELT
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6Y1T
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![BU of 6y1t by Molmil](/molmil-images/mine/6y1t) | The crystal structure of engineered cytochrome c peroxidase from Saccharomyces cerevisiae with a Trp51 to S-Trp51 modification | Descriptor: | 1,2-ETHANEDIOL, Cytochrome c peroxidase, mitochondrial, ... | Authors: | Ortmayer, M, Levy, C, Green, A.P. | Deposit date: | 2020-02-13 | Release date: | 2021-06-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A Noncanonical Tryptophan Analogue Reveals an Active Site Hydrogen Bond Controlling Ferryl Reactivity in a Heme Peroxidase. Jacs Au, 1, 2021
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3KT3
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![BU of 3kt3 by Molmil](/molmil-images/mine/3kt3) | Crystal structure of S. cerevisiae tryptophanyl-tRNA synthetase in complex with TrpAMP | Descriptor: | SULFATE ION, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase, ... | Authors: | Zhou, M, Dong, X, Zhong, C, Shen, N, Ding, J. | Deposit date: | 2009-11-24 | Release date: | 2010-02-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design Nucleic Acids Res., 38, 2010
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