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8ZNE

Cryo-EM structure of W89F mutated Glutamate dehydrogenase from Thermococcus profundus in complex with NADP and GLU in the steady stage of reaction

Summary for 8ZNE
Entry DOI10.2210/pdb8zne/pdb
Related8ZMU
EMDB information60269
DescriptorGlutamate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLUTAMIC ACID, ... (4 entities in total)
Functional Keywordsoxidoreductase, complex, nadp, glutamate, mutant
Biological sourceThermococcus profundus
Total number of polymer chains1
Total formula weight47250.54
Authors
Wakabayashi, T.,Nakasako, M. (deposition date: 2024-05-26, release date: 2024-06-26)
Primary citationWakabayashi, T.,Oide, M.,Matsui, Y.,Nakasako, M.
Mechanism for drastic reduction in catalytic activity of Trp89Phe-mutated glutamate dehydrogenase revealed by cryoEM-sampling metastable conformation in action
To Be Published,
Experimental method
Structure validation

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PDB entries from 2024-08-14

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