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8ZNE

Cryo-EM structure of W89F mutated Glutamate dehydrogenase from Thermococcus profundus in complex with NADP and GLU in the steady stage of reaction

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Glutamate dehydrogenasepolymer41646360.01UniProt (O74024)Thermococcus profundusGDH
2B
(A)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
3C
(A)
GLUTAMIC ACIDnon-polymer147.11Chemie (GLU)
4D
(A)
waterwater18.09Chemie (HOH)
Sequence modifications
A: 4 - 419 (UniProt: O74024)
PDBExternal DatabaseDetails
Phe 89Trp 89engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight46360.0
Non-Polymers*Number of molecules2
Total formula weight890.5
All*Total formula weight47250.5
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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